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==Crystal Structure of Circadian clock protein KaiB from S.Elongatus==
==Crystal Structure of Circadian clock protein KaiB from S.Elongatus==
<StructureSection load='4kso' size='340' side='right' caption='[[4kso]], [[Resolution|resolution]] 2.62&Aring;' scene=''>
<StructureSection load='4kso' size='340' side='right'caption='[[4kso]], [[Resolution|resolution]] 2.62&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4kso]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Synechococcus_elongatus_pcc_7942 Synechococcus elongatus pcc 7942]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KSO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KSO FirstGlance]. <br>
<table><tr><td colspan='2'>[[4kso]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Synechococcus_elongatus_PCC_7942_=_FACHB-805 Synechococcus elongatus PCC 7942 = FACHB-805]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KSO FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2qke|2qke]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.622&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">kaiB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1140 Synechococcus elongatus PCC 7942])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kso OCA], [https://pdbe.org/4kso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kso RCSB], [https://www.ebi.ac.uk/pdbsum/4kso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kso ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kso OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kso RCSB], [http://www.ebi.ac.uk/pdbsum/4kso PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KAIB_SYNE7 KAIB_SYNE7]] Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead need the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC.<ref>PMID:9727980</ref> <ref>PMID:12727878</ref> <ref>PMID:12727879</ref> <ref>PMID:14709675</ref>
[https://www.uniprot.org/uniprot/KAIB_SYNE7 KAIB_SYNE7] Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead need the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC.<ref>PMID:9727980</ref> <ref>PMID:12727878</ref> <ref>PMID:12727879</ref> <ref>PMID:14709675</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4kso" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Circadian clock protein|Circadian clock protein]]
*[[Circadian clock protein 3D structures|Circadian clock protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Synechococcus elongatus pcc 7942]]
[[Category: Large Structures]]
[[Category: Egli, M]]
[[Category: Synechococcus elongatus PCC 7942 = FACHB-805]]
[[Category: Pattanayek, R]]
[[Category: Egli M]]
[[Category: Circadian clock]]
[[Category: Pattanayek R]]
[[Category: Circadian clock protein]]
[[Category: Cyanobacterial circadian clock protein kaib]]
[[Category: Kaic protein]]
[[Category: Soluble]]
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