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==Crystal structure of Q9KD89 from Bacillus halodurans. Northeast Structural Genomics target BhR21==
==Crystal structure of Q9KD89 from Bacillus halodurans. Northeast Structural Genomics target BhR21==
<StructureSection load='2o5a' size='340' side='right' caption='[[2o5a]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='2o5a' size='340' side='right'caption='[[2o5a]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2o5a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_halodurans Bacillus halodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O5A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O5A FirstGlance]. <br>
<table><tr><td colspan='2'>[[2o5a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans Alkalihalobacillus halodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O5A FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BH1328 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=86665 Bacillus halodurans])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o5a OCA], [https://pdbe.org/2o5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o5a RCSB], [https://www.ebi.ac.uk/pdbsum/2o5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o5a ProSAT], [https://www.topsan.org/Proteins/NESGC/2o5a TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o5a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2o5a RCSB], [http://www.ebi.ac.uk/pdbsum/2o5a PDBsum], [http://www.topsan.org/Proteins/NESGC/2o5a TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IOJAP_HALH5 IOJAP_HALH5] Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.[HAMAP-Rule:MF_01477]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o5/2o5a_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o5/2o5a_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2o5a ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus halodurans]]
[[Category: Alkalihalobacillus halodurans]]
[[Category: Acton, T B]]
[[Category: Large Structures]]
[[Category: Baran, M C]]
[[Category: Acton TB]]
[[Category: Benach, J]]
[[Category: Baran MC]]
[[Category: Cunningham, K]]
[[Category: Benach J]]
[[Category: Ho, C H]]
[[Category: Cunningham K]]
[[Category: Hunt, J F]]
[[Category: Ho CH]]
[[Category: Janjua, H]]
[[Category: Hunt JF]]
[[Category: Liu, J]]
[[Category: Janjua H]]
[[Category: Ma, L C]]
[[Category: Liu J]]
[[Category: Montelione, G T]]
[[Category: Ma L-C]]
[[Category: Structural genomic]]
[[Category: Montelione GT]]
[[Category: Rost, B]]
[[Category: Rost B]]
[[Category: Seetharaman, J]]
[[Category: Seetharaman J]]
[[Category: Su, M]]
[[Category: Su M]]
[[Category: Tong, L]]
[[Category: Tong L]]
[[Category: Xiao, R]]
[[Category: Xiao R]]
[[Category: Bhr21]]
[[Category: Nesg]]
[[Category: PSI, Protein structure initiative]]
[[Category: Unknown function]]

Latest revision as of 05:23, 17 October 2024

Crystal structure of Q9KD89 from Bacillus halodurans. Northeast Structural Genomics target BhR21

2o5a, resolution 2.70Å

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