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[[Image:2for.jpg|left|200px]]


{{Structure
==Crystal Structure of the Shigella flexneri Farnesyl Pyrophosphate Synthase Complex with an Isopentenyl Pyrophosphate==
|PDB= 2for |SIZE=350|CAPTION= <scene name='initialview01'>2for</scene>, resolution 2.00&Aring;
<StructureSection load='2for' size='340' side='right'caption='[[2for]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> and <scene name='pdbligand=IPR:ISOPENTYL PYROPHOSPHATE'>IPR</scene>
<table><tr><td colspan='2'>[[2for]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FOR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FOR FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Geranyltranstransferase Geranyltranstransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.10 2.5.1.10]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
|GENE= AAP15892 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=623 Shigella flexneri])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPR:ISOPENTYL+PYROPHOSPHATE'>IPR</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2for FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2for OCA], [https://pdbe.org/2for PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2for RCSB], [https://www.ebi.ac.uk/pdbsum/2for PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2for ProSAT], [https://www.topsan.org/Proteins/MCSG/2for TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0H2UXE9_SHIFL A0A0H2UXE9_SHIFL]  
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fo/2for_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2for ConSurf].
<div style="clear:both"></div>


'''Crystal Structure of the Shigella flexneri Farnesyl Pyrophosphate Synthase Complex with an Isopentenyl Pyrophosphate'''
==See Also==
 
*[[Farnesyl diphosphate synthase 3D structures|Farnesyl diphosphate synthase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2FOR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FOR OCA].
[[Category: Large Structures]]
[[Category: Geranyltranstransferase]]
[[Category: Shigella flexneri]]
[[Category: Shigella flexneri]]
[[Category: Single protein]]
[[Category: Anderson WF]]
[[Category: Anderson, W F.]]
[[Category: Brunzelle JS]]
[[Category: Brunzelle, J S.]]
[[Category: Collart FR]]
[[Category: Collart, F R.]]
[[Category: Joachimiak A]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Minasov G]]
[[Category: Minasov, G.]]
[[Category: Shuvalova L]]
[[Category: Shuvalova, L.]]
[[Category: IPR]]
[[Category: PO4]]
[[Category: bisphosphonate; isoprenyl synthase]]
[[Category: mcsg]]
[[Category: midwest center for structural genomic]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:55:00 2008''
Retrieved from "https://proteopedia.org/2for"