2mxb: Difference between revisions
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New page: '''Unreleased structure''' The entry 2mxb is ON HOLD Authors: Li, Q., Wong, Y., Lee, M., Kang, C. Description: Structure of the transmembrane domain of the erythropoietin receptor [[Ca... |
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==Structure of the transmembrane domain of the mouse erythropoietin receptor== | |||
<StructureSection load='2mxb' size='340' side='right'caption='[[2mxb]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2mxb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MXB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MXB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mxb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mxb OCA], [https://pdbe.org/2mxb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mxb RCSB], [https://www.ebi.ac.uk/pdbsum/2mxb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mxb ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/EPOR_MOUSE EPOR_MOUSE] Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.<ref>PMID:8382775</ref> <ref>PMID:8617735</ref> | |||
==See Also== | |||
*[[Erythropoietin receptor|Erythropoietin receptor]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: Kang | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: Kang C]] | |||
[[Category: Lee M]] | |||
[[Category: Li Q]] | |||
[[Category: Wong Y]] | |||
Latest revision as of 07:02, 1 May 2024
Structure of the transmembrane domain of the mouse erythropoietin receptor
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