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==Crystal structure of the Candida albicans methionine synthase by surface entropy reduction, alanine variant with zinc==
==Crystal structure of the Candida albicans methionine synthase by surface entropy reduction, alanine variant with zinc==
<StructureSection load='3ppg' size='340' side='right' caption='[[3ppg]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
<StructureSection load='3ppg' size='340' side='right'caption='[[3ppg]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ppg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PPG FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ppg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PPG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.98&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ppc|3ppc]], [[3ppf|3ppf]], [[3pph|3pph]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CaO19.10083, CaO19.2551, MET6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5476 Candida albicans])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ppg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ppg OCA], [https://pdbe.org/3ppg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ppg RCSB], [https://www.ebi.ac.uk/pdbsum/3ppg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ppg ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ppg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ppg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ppg RCSB], [http://www.ebi.ac.uk/pdbsum/3ppg PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/METE_CANAL METE_CANAL] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.[HAMAP-Rule:MF_00172]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3ppg" style="background-color:#fffaf0;"></div>
==See Also==
*[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]
[[Category: Candida albicans]]
[[Category: Candida albicans]]
[[Category: Kavanagh, K]]
[[Category: Large Structures]]
[[Category: Monzingo, A F]]
[[Category: Kavanagh K]]
[[Category: Robertus, J D]]
[[Category: Monzingo AF]]
[[Category: Ubhi, D]]
[[Category: Robertus JD]]
[[Category: Cobalamin-independent]]
[[Category: Ubhi D]]
[[Category: Metalloproteinase]]
[[Category: Methyltransferase]]
[[Category: Surface entropy reduction]]
[[Category: Transferase]]

Latest revision as of 09:58, 6 September 2023

Crystal structure of the Candida albicans methionine synthase by surface entropy reduction, alanine variant with zinc

3ppg, resolution 1.98Å

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