3izd: Difference between revisions

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==Model of the large subunit RNA expansion segment ES27L-out based on a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome. 3IZD is a small part (an expansion segment) which is in an alternative conformation to what is in already 3IZF.==
==Model of the large subunit RNA expansion segment ES27L-out based on a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome. 3IZD is a small part (an expansion segment) which is in an alternative conformation to what is in already 3IZF.==
<StructureSection load='3izd' size='340' side='right' caption='[[3izd]], [[Resolution|resolution]] 8.60&Aring;' scene=''>
<SX load='3izd' size='340' side='right' viewer='molstar' caption='[[3izd]], [[Resolution|resolution]] 8.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3izd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IZD FirstGlance]. <br>
<table><tr><td colspan='2'>[[3izd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IZD FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3iz5|3iz5]], [[3iz6|3iz6]], [[3iz7|3iz7]], [[3iz9|3iz9]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 8.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3izd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3izd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3izd RCSB], [http://www.ebi.ac.uk/pdbsum/3izd PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3izd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3izd OCA], [https://pdbe.org/3izd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3izd RCSB], [https://www.ebi.ac.uk/pdbsum/3izd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3izd ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Protein biosynthesis, the translation of the genetic code into polypeptides, occurs on ribonucleoprotein particles called ribosomes. Although X-ray structures of bacterial ribosomes are available, high-resolution structures of eukaryotic 80S ribosomes are lacking. Using cryoelectron microscopy and single-particle reconstruction, we have determined the structure of a translating plant (Triticum aestivum) 80S ribosome at 5.5-A resolution. This map, together with a 6.1-A map of a Saccharomyces cerevisiae 80S ribosome, has enabled us to model approximately 98% of the rRNA. Accurate assignment of the rRNA expansion segments (ES) and variable regions has revealed unique ES-ES and r-protein-ES interactions, providing insight into the structure and evolution of the eukaryotic ribosome.
Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.,Armache JP, Jarasch A, Anger AM, Villa E, Becker T, Bhushan S, Jossinet F, Habeck M, Dindar G, Franckenberg S, Marquez V, Mielke T, Thomm M, Berninghausen O, Beatrix B, Soding J, Westhof E, Wilson DN, Beckmann R Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19748-53. Epub 2010 Oct 27. PMID:20980660<ref>PMID:20980660</ref>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</SX>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Anger, A M]]
[[Category: Anger AM]]
[[Category: Armache, J P]]
[[Category: Armache J-P]]
[[Category: Beatrix, B]]
[[Category: Beatrix B]]
[[Category: Becker, T]]
[[Category: Becker T]]
[[Category: Beckmann, R]]
[[Category: Beckmann R]]
[[Category: Berninghausen, O]]
[[Category: Berninghausen O]]
[[Category: Bhushan, S]]
[[Category: Bhushan S]]
[[Category: Dindar, G]]
[[Category: Dindar G]]
[[Category: Franckenberg, S]]
[[Category: Franckenberg S]]
[[Category: Habeck, M]]
[[Category: Habeck M]]
[[Category: Jarasch, A]]
[[Category: Jarasch A]]
[[Category: Jossinet, F]]
[[Category: Jossinet F]]
[[Category: Marquez, V]]
[[Category: Marquez V]]
[[Category: Mielke, T]]
[[Category: Mielke T]]
[[Category: Soeding, J]]
[[Category: Soeding J]]
[[Category: Thomm, M]]
[[Category: Thomm M]]
[[Category: Villa, E]]
[[Category: Villa E]]
[[Category: Westhof, E]]
[[Category: Westhof E]]
[[Category: Wilson, D N]]
[[Category: Wilson DN]]
[[Category: De novo modeling]]
[[Category: Eukaryotic ribosome]]
[[Category: Homology modelling]]
[[Category: Ribosomal rna]]
[[Category: Ribosome]]
[[Category: Rna expansion segment]]
[[Category: Rrna]]

Latest revision as of 10:08, 21 February 2024

Model of the large subunit RNA expansion segment ES27L-out based on a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome. 3IZD is a small part (an expansion segment) which is in an alternative conformation to what is in already 3IZF.

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