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==Structure of Tetracycline repressor in complex with antiinducer peptide-TAP1==
==Structure of Tetracycline repressor in complex with antiinducer peptide-TAP1==
<StructureSection load='3zqf' size='340' side='right' caption='[[3zqf]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
<StructureSection load='3zqf' size='340' side='right'caption='[[3zqf]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3zqf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZQF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZQF FirstGlance]. <br>
<table><tr><td colspan='2'>[[3zqf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZQF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZQF FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xgc|2xgc]], [[2xpw|2xpw]], [[2x9d|2x9d]], [[1bjz|1bjz]], [[3zqg|3zqg]], [[3zqh|3zqh]], [[2trt|2trt]], [[2xpv|2xpv]], [[2vkv|2vkv]], [[1ork|1ork]], [[2xge|2xge]], [[2x6o|2x6o]], [[1a6i|1a6i]], [[2vke|2vke]], [[1qpi|1qpi]], [[2xgd|2xgd]], [[1du7|1du7]], [[2xrl|2xrl]], [[2xpt|2xpt]], [[2xpu|2xpu]], [[2xb5|2xb5]], [[2xps|2xps]], [[3zqi|3zqi]], [[1bj0|1bj0]], [[2tct|2tct]], [[1bjy|1bjy]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.56&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zqf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zqf RCSB], [http://www.ebi.ac.uk/pdbsum/3zqf PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zqf OCA], [https://pdbe.org/3zqf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zqf RCSB], [https://www.ebi.ac.uk/pdbsum/3zqf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zqf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TETR2_ECOLX TETR2_ECOLX] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.[https://www.uniprot.org/uniprot/TETR4_ECOLX TETR4_ECOLX] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3zqf" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Tetracycline repressor protein|Tetracycline repressor protein]]
*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Berens, C]]
[[Category: Large Structures]]
[[Category: Goeke, D]]
[[Category: Berens C]]
[[Category: Goetz, C]]
[[Category: Goeke D]]
[[Category: Grubmueller, S]]
[[Category: Goetz C]]
[[Category: Hillen, W]]
[[Category: Grubmueller S]]
[[Category: Kaspar, D]]
[[Category: Hillen W]]
[[Category: Klotzsche, M]]
[[Category: Kaspar D]]
[[Category: Muller, Y A]]
[[Category: Klotzsche M]]
[[Category: Sevvana, M]]
[[Category: Muller YA]]
[[Category: Stoeckle, C]]
[[Category: Sevvana M]]
[[Category: Wimmer, C]]
[[Category: Stoeckle C]]
[[Category: Allostery]]
[[Category: Wimmer C]]
[[Category: Inducer]]
[[Category: Peptidic effector]]
[[Category: Tetr]]
[[Category: Tetracycline repressor]]
[[Category: Transcription]]
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