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==Crystal Structure of MjTX-I, a myotoxic Lys49-phospholipase A2 from Bothrops moojeni==
==Crystal Structure of MjTX-I, a myotoxic Lys49-phospholipase A2 from Bothrops moojeni==
<StructureSection load='3t0r' size='340' side='right' caption='[[3t0r]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
<StructureSection load='3t0r' size='340' side='right'caption='[[3t0r]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3t0r]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bothrops_moojeni Bothrops moojeni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T0R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T0R FirstGlance]. <br>
<table><tr><td colspan='2'>[[3t0r]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bothrops_moojeni Bothrops moojeni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T0R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T0R FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.49&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3i3h|3i3h]], [[2q2j|2q2j]], [[1pa0|1pa0]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t0r OCA], [https://pdbe.org/3t0r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t0r RCSB], [https://www.ebi.ac.uk/pdbsum/3t0r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t0r ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t0r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t0r RCSB], [http://www.ebi.ac.uk/pdbsum/3t0r PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PA2H1_BOTMO PA2H1_BOTMO] Snake venom phospholipase A2 homolog that displays local myotoxin and edema-inducing activities and is lethal by intraperitoneal injection.<ref>PMID:10620318</ref>
==See Also==
*[[Phospholipase A2 homolog|Phospholipase A2 homolog]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bothrops moojeni]]
[[Category: Bothrops moojeni]]
[[Category: Fontes, M R.M]]
[[Category: Large Structures]]
[[Category: Marchi-Salvador, D P]]
[[Category: Fontes MRM]]
[[Category: Salvador, G H.M]]
[[Category: Marchi-Salvador DP]]
[[Category: Lys49-phospholipase a2]]
[[Category: Salvador GHM]]
[[Category: Myotoxin]]
[[Category: Toxin]]
[[Category: Venom gland]]