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==Directed evolution and rational design of a de novo designed esterase toward improved catalysis. Northeast Structural Genomics Consortium (NESG) Target OR184==
==Directed evolution and rational design of a de novo designed esterase toward improved catalysis. Northeast Structural Genomics Consortium (NESG) Target OR184==
<StructureSection load='4jxi' size='340' side='right' caption='[[4jxi]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
<StructureSection load='4jxi' size='340' side='right'caption='[[4jxi]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4jxi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JXI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JXI FirstGlance]. <br>
<table><tr><td colspan='2'>[[4jxi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JXI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JXI FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PE5:3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL'>PE5</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.29&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PE5:3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL'>PE5</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3u10|3u10]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jxi OCA], [https://pdbe.org/4jxi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jxi RCSB], [https://www.ebi.ac.uk/pdbsum/4jxi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jxi ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jxi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jxi RCSB], [http://www.ebi.ac.uk/pdbsum/4jxi PDBsum]</span></td></tr>
</table>
</table>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Synthetic construct]]
[[Category: Baker, D]]
[[Category: Baker D]]
[[Category: Bryan, C]]
[[Category: Bryan C]]
[[Category: Everett, J K]]
[[Category: Everett JK]]
[[Category: Hilvert, D]]
[[Category: Hilvert D]]
[[Category: Hunt, J F]]
[[Category: Hunt JF]]
[[Category: Kiss, G]]
[[Category: Kiss G]]
[[Category: Kohan, E]]
[[Category: Kohan E]]
[[Category: Kornhaber, G]]
[[Category: Kornhaber G]]
[[Category: Kuzin, A]]
[[Category: Kuzin A]]
[[Category: Lech, Z]]
[[Category: Lech Z]]
[[Category: Lew, S]]
[[Category: Lew S]]
[[Category: Maglaqui, M]]
[[Category: Maglaqui M]]
[[Category: Montelione, G T]]
[[Category: Montelione GT]]
[[Category: Moretti, R]]
[[Category: Moretti R]]
[[Category: Structural genomic]]
[[Category: Nguyen R]]
[[Category: Nguyen, R]]
[[Category: Pande V]]
[[Category: Pande, V]]
[[Category: Richter F]]
[[Category: Richter, F]]
[[Category: Seetharaman R]]
[[Category: Seetharaman, R]]
[[Category: Smith M]]
[[Category: Smith, M]]
[[Category: Smith MD]]
[[Category: Smith, M D]]
[[Category: Tong L]]
[[Category: Tong, L]]
[[Category: Xiao R]]
[[Category: Xiao, R]]
[[Category: Nesg]]
[[Category: PSI, Protein structure initiative]]
[[Category: Psi-biology]]
[[Category: Unknown function]]