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==Crystal Structure of Adenylosuccinate Lyase from Francisella tularensis Complexed with AMP and Succinate==
==Crystal Structure of Adenylosuccinate Lyase from Francisella tularensis Complexed with AMP and Succinate==
<StructureSection load='4eei' size='340' side='right' caption='[[4eei]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
<StructureSection load='4eei' size='340' side='right'caption='[[4eei]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4eei]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Francisella_tularensis_subsp._tularensis_schu_s4 Francisella tularensis subsp. tularensis schu s4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EEI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EEI FirstGlance]. <br>
<table><tr><td colspan='2'>[[4eei]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Francisella_tularensis_subsp._tularensis_SCHU_S4 Francisella tularensis subsp. tularensis SCHU S4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EEI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EEI FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.921&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FTT_0015, purB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=177416 Francisella tularensis subsp. tularensis SCHU S4])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenylosuccinate_lyase Adenylosuccinate lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.2.2 4.3.2.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eei OCA], [https://pdbe.org/4eei PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eei RCSB], [https://www.ebi.ac.uk/pdbsum/4eei PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eei ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eei OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eei RCSB], [http://www.ebi.ac.uk/pdbsum/4eei PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q5NIQ1_FRATT Q5NIQ1_FRATT]
==See Also==
*[[Adenylosuccinate lyase 3D structures|Adenylosuccinate lyase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Adenylosuccinate lyase]]
[[Category: Francisella tularensis subsp. tularensis SCHU S4]]
[[Category: Francisella tularensis subsp. tularensis schu s4]]
[[Category: Large Structures]]
[[Category: Anderson, W F]]
[[Category: Anderson WF]]
[[Category: Structural genomic]]
[[Category: Joachimiak A]]
[[Category: Joachimiak, A]]
[[Category: Kim Y]]
[[Category: Kim, Y]]
[[Category: Maltseva N]]
[[Category: Maltseva, N]]
[[Category: Shatsman S]]
[[Category: Shatsman, S]]
[[Category: Alpha structure]]
[[Category: Amp binding]]
[[Category: Beta-elimination]]
[[Category: Csgid]]
[[Category: Cytosole]]
[[Category: Lyase]]
[[Category: National institute of allergy and infectious disease]]
[[Category: Niaid]]

Latest revision as of 14:59, 14 March 2024

Crystal Structure of Adenylosuccinate Lyase from Francisella tularensis Complexed with AMP and Succinate

4eei, resolution 1.92Å

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