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==Crystal structure of Maleylacetoacetate isomerase from Anaeromyxobacter dehalogenans 2CP-1, TARGET EFI-507175, with bound dicarboxyethyl glutathione and citrate in the active site==
==Crystal structure of Maleylacetoacetate isomerase from Anaeromyxobacter dehalogenans 2CP-1, TARGET EFI-507175, with bound dicarboxyethyl glutathione and citrate in the active site==
<StructureSection load='4kae' size='340' side='right' caption='[[4kae]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='4kae' size='340' side='right'caption='[[4kae]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4kae]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Anaeromyxobacter_dehalogenans_2cp-1 Anaeromyxobacter dehalogenans 2cp-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KAE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KAE FirstGlance]. <br>
<table><tr><td colspan='2'>[[4kae]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Anaeromyxobacter_dehalogenans_2CP-1 Anaeromyxobacter dehalogenans 2CP-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KAE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KAE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TGG:GAMMA-GLUTAMYL-S-(1,2-DICARBOXYETHYL)CYSTEINYLGLYCINE'>TGG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4igj|4igj]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TGG:GAMMA-GLUTAMYL-S-(1,2-DICARBOXYETHYL)CYSTEINYLGLYCINE'>TGG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">A2cp1_3570 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=455488 Anaeromyxobacter dehalogenans 2CP-1])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kae FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kae OCA], [https://pdbe.org/4kae PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kae RCSB], [https://www.ebi.ac.uk/pdbsum/4kae PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kae ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Maleylacetoacetate_isomerase Maleylacetoacetate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.2 5.2.1.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kae FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kae OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kae RCSB], [http://www.ebi.ac.uk/pdbsum/4kae PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/B8J605_ANAD2 B8J605_ANAD2]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Anaeromyxobacter dehalogenans 2cp-1]]
[[Category: Anaeromyxobacter dehalogenans 2CP-1]]
[[Category: Maleylacetoacetate isomerase]]
[[Category: Large Structures]]
[[Category: Almo, S C]]
[[Category: Al Obaidi NF]]
[[Category: Bhosle, R]]
[[Category: Almo SC]]
[[Category: Chowdhury, S]]
[[Category: Bhosle R]]
[[Category: Evans, B]]
[[Category: Chowdhury S]]
[[Category: Gerlt, J A]]
[[Category: Evans B]]
[[Category: Glenn, A Scott]]
[[Category: Gerlt JA]]
[[Category: Hammonds, J]]
[[Category: Hammonds J]]
[[Category: Hillerich, B]]
[[Category: Hillerich B]]
[[Category: Imker, H J]]
[[Category: Imker HJ]]
[[Category: Initiative, Enzyme Function]]
[[Category: Kim J]]
[[Category: Kim, J]]
[[Category: Love J]]
[[Category: Love, J]]
[[Category: Morisco LL]]
[[Category: Morisco, L L]]
[[Category: Scott Glenn A]]
[[Category: Obaidi, N F.Al]]
[[Category: Seidel RD]]
[[Category: Seidel, R D]]
[[Category: Sojitra S]]
[[Category: Sojitra, S]]
[[Category: Stead M]]
[[Category: Stead, M]]
[[Category: Toro R]]
[[Category: Toro, R]]
[[Category: Washington E]]
[[Category: Washington, E]]
[[Category: Wasserman SR]]
[[Category: Wasserman, S R]]
[[Category: Enzyme function initiative]]
[[Category: Glutathione]]
[[Category: Isomerase]]
[[Category: Structural genomic]]

Latest revision as of 15:56, 20 September 2023

Crystal structure of Maleylacetoacetate isomerase from Anaeromyxobacter dehalogenans 2CP-1, TARGET EFI-507175, with bound dicarboxyethyl glutathione and citrate in the active site

4kae, resolution 1.50Å

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