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==Crystal structure of Spodoptera frugiperda DNMT2 E260A/E261A/K263A mutant==
==Crystal structure of Spodoptera frugiperda DNMT2 E260A/E261A/K263A mutant==
<StructureSection load='4h0n' size='340' side='right' caption='[[4h0n]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
<StructureSection load='4h0n' size='340' side='right'caption='[[4h0n]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4h0n]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Spodoptera_frugiperda Spodoptera frugiperda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H0N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H0N FirstGlance]. <br>
<table><tr><td colspan='2'>[[4h0n]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Spodoptera_frugiperda Spodoptera frugiperda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H0N FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.712&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DNMT2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7108 Spodoptera frugiperda])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h0n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h0n RCSB], [http://www.ebi.ac.uk/pdbsum/4h0n PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h0n OCA], [https://pdbe.org/4h0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h0n RCSB], [https://www.ebi.ac.uk/pdbsum/4h0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h0n ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TRDMT_SPOFR TRDMT_SPOFR] Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp) (By similarity). Also has DNA (cytosine-5)-methyltransferase activity (PubMed:23103599). Shows affinity for both tRNA(Asp) and DNA substrates (PubMed:23103599).[UniProtKB:O14717]<ref>PMID:23103599</ref>


==See Also==
==See Also==
*[[DNA methyltransferase|DNA methyltransferase]]
*[[DNA methyltransferase 3D structures|DNA methyltransferase 3D structures]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Spodoptera frugiperda]]
[[Category: Spodoptera frugiperda]]
[[Category: Ding, J]]
[[Category: Ding J]]
[[Category: Du, J]]
[[Category: Du J]]
[[Category: Li, S]]
[[Category: Li S]]
[[Category: Yang, H]]
[[Category: Yang H]]
[[Category: Yin, J]]
[[Category: Yin J]]
[[Category: Zhong, J]]
[[Category: Zhong J]]
[[Category: Sah binding]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/4h0n"