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==Crystal structure of the E. coli thiM riboswitch in complex with thiamine==
==Crystal structure of the E. coli thiM riboswitch in complex with thiamine==
<StructureSection load='4nyg' size='340' side='right' caption='[[4nyg]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
<StructureSection load='4nyg' size='340' side='right'caption='[[4nyg]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4nyg]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NYG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NYG FirstGlance]. <br>
<table><tr><td colspan='2'>[[4nyg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NYG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NYG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=VIB:3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM'>VIB</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.05&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=A23:ADENOSINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>A23</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A23:ADENOSINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>A23</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=VIB:3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM'>VIB</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4nya|4nya]], [[4nyb|4nyb]], [[4nyc|4nyc]], [[4nyd|4nyd]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nyg OCA], [https://pdbe.org/4nyg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nyg RCSB], [https://www.ebi.ac.uk/pdbsum/4nyg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nyg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nyg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nyg RCSB], [http://www.ebi.ac.uk/pdbsum/4nyg PDBsum]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4nyg" style="background-color:#fffaf0;"></div>
==See Also==
*[[Riboswitch 3D structures|Riboswitch 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Abell, C]]
[[Category: Escherichia coli]]
[[Category: Amare, A R.Ferre-D]]
[[Category: Large Structures]]
[[Category: Homan, P]]
[[Category: Abell C]]
[[Category: Smith, A G]]
[[Category: Ferre-D'Amare AR]]
[[Category: Warner, K D]]
[[Category: Homan P]]
[[Category: Weeks, K M]]
[[Category: Smith AG]]
[[Category: Fragment-based drug discovery]]
[[Category: Warner KD]]
[[Category: Riboswitch]]
[[Category: Weeks KM]]
[[Category: Rna]]

Latest revision as of 17:04, 20 September 2023

Crystal structure of the E. coli thiM riboswitch in complex with thiamine

4nyg, resolution 3.05Å

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