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[[Image:2hj0.gif|left|200px]]


{{Structure
==Crystal Structure of the Putative Alfa Subunit of Citrate Lyase in Complex with Citrate from Streptococcus mutans, Northeast Structural Genomics Target SmR12 .==
|PDB= 2hj0 |SIZE=350|CAPTION= <scene name='initialview01'>2hj0</scene>, resolution 2.70&Aring;
<StructureSection load='2hj0' size='340' side='right'caption='[[2hj0]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CIT:CITRIC ACID'>CIT</scene>
<table><tr><td colspan='2'>[[2hj0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_mutans_UA159 Streptococcus mutans UA159]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HJ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HJ0 FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Citrate_(pro-3S)-lyase Citrate (pro-3S)-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.6 4.1.3.6]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
|GENE= cilA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 Streptococcus mutans])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hj0 OCA], [https://pdbe.org/2hj0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hj0 RCSB], [https://www.ebi.ac.uk/pdbsum/2hj0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hj0 ProSAT], [https://www.topsan.org/Proteins/NESGC/2hj0 TOPSAN]</span></td></tr>
 
</table>
'''Crystal Structure of the Putative Alfa Subunit of Citrate Lyase in Complex with Citrate from Streptococcus mutans, Northeast Structural Genomics Target SmR12 (CASP Target).'''
== Function ==
 
[https://www.uniprot.org/uniprot/Q8DUC1_STRMU Q8DUC1_STRMU]
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2HJ0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HJ0 OCA].  
Check<jmol>
[[Category: Citrate (pro-3S)-lyase]]
  <jmolCheckbox>
[[Category: Single protein]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hj/2hj0_consurf.spt"</scriptWhenChecked>
[[Category: Streptococcus mutans]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Acton, T B.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Baran, M.]]
  </jmolCheckbox>
[[Category: Cunningham, K.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hj0 ConSurf].
[[Category: Forouhar, F.]]
<div style="clear:both"></div>
[[Category: Hunt, J F.]]
__TOC__
[[Category: Hussain, M.]]
</StructureSection>
[[Category: Janjua, H.]]
[[Category: Large Structures]]
[[Category: Jayaraman, S.]]
[[Category: Streptococcus mutans UA159]]
[[Category: Liu, J.]]
[[Category: Acton TB]]
[[Category: Ma, L C.]]
[[Category: Baran M]]
[[Category: Montelione, G T.]]
[[Category: Cunningham K]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Forouhar F]]
[[Category: Rost, B.]]
[[Category: Hunt JF]]
[[Category: Shastry, R.]]
[[Category: Hussain M]]
[[Category: Tong, L.]]
[[Category: Janjua H]]
[[Category: Xiao, R.]]
[[Category: Jayaraman S]]
[[Category: CIT]]
[[Category: Liu J]]
[[Category: alpha beta protein.]]
[[Category: Ma LC]]
[[Category: nesg]]
[[Category: Montelione GT]]
[[Category: northeast structural genomics consortium]]
[[Category: Rost B]]
[[Category: protein structure initiative]]
[[Category: Shastry R]]
[[Category: psi-2]]
[[Category: Tong L]]
[[Category: structural genomic]]
[[Category: Xiao R]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:17:43 2008''