2i7a: Difference between revisions

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[[Image:2i7a.gif|left|200px]]


{{Structure
==Domain IV of Human Calpain 13==
|PDB= 2i7a |SIZE=350|CAPTION= <scene name='initialview01'>2i7a</scene>, resolution 1.80&Aring;
<StructureSection load='2i7a' size='340' side='right'caption='[[2i7a]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
<table><tr><td colspan='2'>[[2i7a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I7A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I7A FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
|GENE= CAPN13 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i7a OCA], [https://pdbe.org/2i7a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i7a RCSB], [https://www.ebi.ac.uk/pdbsum/2i7a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i7a ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CAN13_HUMAN CAN13_HUMAN] Probable non-lysosomal thiol-protease.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i7/2i7a_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i7a ConSurf].
<div style="clear:both"></div>


'''Domain IV of Human Calpain 13'''
==See Also==
 
*[[Calpain 3D structures|Calpain 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2I7A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I7A OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith CH]]
[[Category: Bochkarev, A.]]
[[Category: Bochkarev A]]
[[Category: Butler-cole, C.]]
[[Category: Butler-cole C]]
[[Category: Davis, T L]]
[[Category: Davis TL]]
[[Category: Dhe-Paganon, S.]]
[[Category: Dhe-Paganon S]]
[[Category: Edwards, A M.]]
[[Category: Edwards AM]]
[[Category: Jr., P J.Finerty.]]
[[Category: Finerty Jr PJ]]
[[Category: Newman, E M.]]
[[Category: Newman EM]]
[[Category: Ng, K.]]
[[Category: Ng K]]
[[Category: Ravulapalli, R.]]
[[Category: Ravulapalli R]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Sundstrom M]]
[[Category: Sundstrom, M.]]
[[Category: Walker JR]]
[[Category: Walker, J R.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: CA]]
[[Category: GOL]]
[[Category: SO4]]
[[Category: calcium-dependent cytoplasmic cysteine proteinase]]
[[Category: calpain]]
[[Category: ef-hand]]
[[Category: papain-like]]
[[Category: sgc]]
[[Category: structural genomic]]
[[Category: structural genomics consortium]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:26:17 2008''
Retrieved from "https://proteopedia.org/2i7a"