2i7p: Difference between revisions
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==Crystal structure of human PANK3 in complex with AcCoA== | |||
<StructureSection load='2i7p' size='340' side='right'caption='[[2i7p]], [[Resolution|resolution]] 2.05Å' scene=''> | |||
| | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2i7p]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I7P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I7P FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | |||
| | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i7p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i7p OCA], [https://pdbe.org/2i7p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i7p RCSB], [https://www.ebi.ac.uk/pdbsum/2i7p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i7p ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PANK3_HUMAN PANK3_HUMAN] Plays a role in the physiological regulation of the intracellular CoA concentration (By similarity). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i7/2i7p_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i7p ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Pantothenate kinase 3D structures|Pantothenate kinase 3D structures]] | |||
__TOC__ | |||
== | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Arrowsmith CH]] | |||
[[Category: Arrowsmith | [[Category: Bochkarev A]] | ||
[[Category: Bochkarev | [[Category: Edwards AM]] | ||
[[Category: Edwards | [[Category: Finerty P]] | ||
[[Category: Finerty | [[Category: Hong BS]] | ||
[[Category: Hong | [[Category: Loppnau P]] | ||
[[Category: Loppnau | [[Category: Park HW]] | ||
[[Category: Park | [[Category: Shen L]] | ||
[[Category: Sundstrom M]] | |||
[[Category: Shen | [[Category: Tempel W]] | ||
[[Category: Sundstrom | [[Category: Wang L]] | ||
[[Category: Tempel | [[Category: Weigelt J]] | ||
[[Category: Wang | |||
[[Category: Weigelt | |||
Latest revision as of 09:02, 21 February 2024
Crystal structure of human PANK3 in complex with AcCoA
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