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[[Image:2icp.gif|left|200px]]


{{Structure
==Crystal structure of the bacterial antitoxin HigA from Escherichia coli at pH 4.0. Northeast Structural Genomics Consortium TARGET ER390.==
|PDB= 2icp |SIZE=350|CAPTION= <scene name='initialview01'>2icp</scene>, resolution 1.880&Aring;
<StructureSection load='2icp' size='340' side='right'caption='[[2icp]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
|SITE=
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM ION'>MG</scene>
<table><tr><td colspan='2'>[[2icp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_CFT073 Escherichia coli CFT073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ICP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ICP FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
|GENE= higa ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2icp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2icp OCA], [https://pdbe.org/2icp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2icp RCSB], [https://www.ebi.ac.uk/pdbsum/2icp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2icp ProSAT], [https://www.topsan.org/Proteins/NESGC/2icp TOPSAN]</span></td></tr>
 
</table>
'''Crystal structure of the bacterial antitoxin HigA from Escherichia coli at pH 4.0. Northeast Structural Genomics Consortium TARGET ER390.'''
== Function ==
 
[https://www.uniprot.org/uniprot/YDDM_ECOL6 YDDM_ECOL6]  
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2ICP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ICP OCA].  
Check<jmol>
[[Category: Escherichia coli]]
  <jmolCheckbox>
[[Category: Single protein]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ic/2icp_consurf.spt"</scriptWhenChecked>
[[Category: Abashidze, M.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Acton, T B.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Arbing, M A.]]
  </jmolCheckbox>
[[Category: Baran, M C.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2icp ConSurf].
[[Category: Cunningham, K.]]
<div style="clear:both"></div>
[[Category: Hunt, J F.]]
__TOC__
[[Category: Hurley, J M.]]
</StructureSection>
[[Category: Inouye, M.]]
[[Category: Escherichia coli CFT073]]
[[Category: Janjua, H.]]
[[Category: Large Structures]]
[[Category: Liu, J.]]
[[Category: Abashidze M]]
[[Category: Ma, L C.]]
[[Category: Acton TB]]
[[Category: Montelione, G T.]]
[[Category: Arbing MA]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Baran MC]]
[[Category: Rost, B.]]
[[Category: Cunningham K]]
[[Category: Woychik, N A.]]
[[Category: Hunt JF]]
[[Category: Xiao, R.]]
[[Category: Hurley JM]]
[[Category: Zhao, L.]]
[[Category: Inouye M]]
[[Category: MG]]
[[Category: Janjua H]]
[[Category: helix-turn-helix]]
[[Category: Liu J]]
[[Category: nesg]]
[[Category: Ma LC]]
[[Category: northeast structural genomics consortium]]
[[Category: Montelione GT]]
[[Category: protein structure initiative]]
[[Category: Rost B]]
[[Category: psi-2]]
[[Category: Woychik NA]]
[[Category: structural genomic]]
[[Category: Xiao R]]
 
[[Category: Zhao L]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:27:54 2008''
Retrieved from "https://proteopedia.org/2icp"