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[[Image:2iq7.jpg|left|200px]]


{{Structure
==Crystal structure of the polygalacturonase from Colletotrichum lupini and its implications for the interaction with polygalacturonase-inhibiting proteins==
|PDB= 2iq7 |SIZE=350|CAPTION= <scene name='initialview01'>2iq7</scene>, resolution 1.94&Aring;
<StructureSection load='2iq7' size='340' side='right'caption='[[2iq7]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene> and <scene name='pdbligand=ACY:ACETIC ACID'>ACY</scene>
<table><tr><td colspan='2'>[[2iq7]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Colletotrichum_lupini Colletotrichum lupini]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IQ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IQ7 FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Polygalacturonase Polygalacturonase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.15 3.2.1.15]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iq7 OCA], [https://pdbe.org/2iq7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iq7 RCSB], [https://www.ebi.ac.uk/pdbsum/2iq7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iq7 ProSAT]</span></td></tr>
 
</table>
'''Crystal structure of the polygalacturonase from Colletotrichum lupini and its implications for the interaction with polygalacturonase-inhibiting proteins'''
== Function ==
 
[https://www.uniprot.org/uniprot/A1E266_9PEZI A1E266_9PEZI]
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2IQ7 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Colletotrichum_lupini Colletotrichum lupini]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IQ7 OCA].  
Check<jmol>
 
  <jmolCheckbox>
==Reference==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iq/2iq7_consurf.spt"</scriptWhenChecked>
Crystal structure of the endopolygalacturonase from the phytopathogenic fungus Colletotrichum lupini and its interaction with polygalacturonase-inhibiting proteins., Bonivento D, Pontiggia D, Matteo AD, Fernandez-Recio J, Salvi G, Tsernoglou D, Cervone F, Lorenzo GD, Federici L, Proteins. 2008 Jan 1;70(1):294-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17876815 17876815]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iq7 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Colletotrichum lupini]]
[[Category: Colletotrichum lupini]]
[[Category: Polygalacturonase]]
[[Category: Large Structures]]
[[Category: Protein complex]]
[[Category: Bonivento D]]
[[Category: Bonivento, D.]]
[[Category: Federici L]]
[[Category: Federici, L.]]
[[Category: Matteo AD]]
[[Category: Matteo, A D.]]
[[Category: ACY]]
[[Category: PEG]]
[[Category: PG4]]
[[Category: hydrolase]]
[[Category: parallel beta helix]]
 
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