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==The 1.6A crystal structure of the geranyltransferase from Agrobacterium tumefaciens==
==The 1.6A crystal structure of the geranyltransferase from Agrobacterium tumefaciens==
<StructureSection load='2h8o' size='340' side='right' caption='[[2h8o]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='2h8o' size='340' side='right'caption='[[2h8o]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2h8o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Agrobacterium_tumefaciens_str._c58 Agrobacterium tumefaciens str. c58]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H8O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H8O FirstGlance]. <br>
<table><tr><td colspan='2'>[[2h8o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_fabrum_str._C58 Agrobacterium fabrum str. C58]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H8O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H8O FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ispA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=176299 Agrobacterium tumefaciens str. C58])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Geranyltranstransferase Geranyltranstransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.10 2.5.1.10] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h8o OCA], [https://pdbe.org/2h8o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h8o RCSB], [https://www.ebi.ac.uk/pdbsum/2h8o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h8o ProSAT], [https://www.topsan.org/Proteins/MCSG/2h8o TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h8o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2h8o RCSB], [http://www.ebi.ac.uk/pdbsum/2h8o PDBsum], [http://www.topsan.org/Proteins/MCSG/2h8o TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q7CWE5_AGRFC Q7CWE5_AGRFC]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h8/2h8o_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h8/2h8o_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2h8o ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Agrobacterium tumefaciens str. c58]]
[[Category: Agrobacterium fabrum str. C58]]
[[Category: Geranyltranstransferase]]
[[Category: Large Structures]]
[[Category: Edwards, A]]
[[Category: Edwards A]]
[[Category: Gu, J]]
[[Category: Gu J]]
[[Category: Joachimiak, A]]
[[Category: Joachimiak A]]
[[Category: Structural genomic]]
[[Category: Savchenko A]]
[[Category: Savchenko, A]]
[[Category: Xu X]]
[[Category: Xu, X]]
[[Category: Zhang R]]
[[Category: Zhang, R]]
[[Category: Agrobacterium tumefacien]]
[[Category: Geranyltransferase]]
[[Category: Mcsg]]
[[Category: PSI, Protein structure initiative]]
[[Category: Transferase]]

Latest revision as of 09:31, 14 February 2024

The 1.6A crystal structure of the geranyltransferase from Agrobacterium tumefaciens

2h8o, resolution 1.60Å

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