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==Inhibitor Induced Structural Change in the HCV IRES Domain IIa RNA==
==Inhibitor Induced Structural Change in the HCV IRES Domain IIa RNA==
<StructureSection load='2ku0' size='340' side='right' caption='[[2ku0]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='2ku0' size='340' side='right'caption='[[2ku0]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ku0]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KU0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KU0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ku0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KU0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KU0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ISI:(7S)-7-[(DIMETHYLAMINO)METHYL]-1-[3-(DIMETHYLAMINO)PROPYL]-7,8-DIHYDRO-1H-FURO[3,2-E]BENZIMIDAZOL-2-AMINE'>ISI</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ktz|2ktz]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ISI:(7S)-7-[(DIMETHYLAMINO)METHYL]-1-[3-(DIMETHYLAMINO)PROPYL]-7,8-DIHYDRO-1H-FURO[3,2-E]BENZIMIDAZOL-2-AMINE'>ISI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ku0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ku0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ku0 RCSB], [http://www.ebi.ac.uk/pdbsum/2ku0 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ku0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ku0 OCA], [https://pdbe.org/2ku0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ku0 RCSB], [https://www.ebi.ac.uk/pdbsum/2ku0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ku0 ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2ku0" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Davis, D R]]
[[Category: Hepacivirus C]]
[[Category: Griffey, R H]]
[[Category: Large Structures]]
[[Category: III, T E.Cheatham]]
[[Category: Cheatham III TE]]
[[Category: Paulsen, R B]]
[[Category: Davis DR]]
[[Category: Seth, P P]]
[[Category: Griffey RH]]
[[Category: Skalicky, J J]]
[[Category: Paulsen RB]]
[[Category: Swayze, E E]]
[[Category: Seth PP]]
[[Category: Antiviral]]
[[Category: Skalicky JJ]]
[[Category: Hepatitis c virus]]
[[Category: Swayze EE]]
[[Category: Rna]]
[[Category: Rna structure]]