2nu3: Difference between revisions

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[[Image:2nu3.gif|left|200px]]


{{Structure
==Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I==
|PDB= 2nu3 |SIZE=350|CAPTION= <scene name='initialview01'>2nu3</scene>, resolution 1.8&Aring;
<StructureSection load='2nu3' size='340' side='right'caption='[[2nu3]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2nu3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo] and [https://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NU3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NU3 FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Streptogrisin_B Streptogrisin B], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.81 3.4.21.81]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nu3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nu3 OCA], [https://pdbe.org/2nu3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nu3 RCSB], [https://www.ebi.ac.uk/pdbsum/2nu3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nu3 ProSAT]</span></td></tr>
}}
</table>
== Function ==
[https://www.uniprot.org/uniprot/PRTB_STRGR PRTB_STRGR] Has a primary specificity for large aliphatic or aromatic amino acids.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nu/2nu3_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2nu3 ConSurf].
<div style="clear:both"></div>


'''Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I'''
==See Also==
 
*[[Proteinase 3D structures|Proteinase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2NU3 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo] and [http://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NU3 OCA].
[[Category: Large Structures]]
[[Category: Meleagris gallopavo]]
[[Category: Meleagris gallopavo]]
[[Category: Protein complex]]
[[Category: Streptogrisin B]]
[[Category: Streptomyces griseus]]
[[Category: Streptomyces griseus]]
[[Category: Anderson, S.]]
[[Category: Anderson S]]
[[Category: Bateman, K S.]]
[[Category: Bateman KS]]
[[Category: Huang, K.]]
[[Category: Huang K]]
[[Category: James, M N.G.]]
[[Category: James MNG]]
[[Category: Jr., M Laskowski.]]
[[Category: Laskowski Jr M]]
[[Category: Lu, W.]]
[[Category: Lu W]]
[[Category: Qasim, M A.]]
[[Category: Qasim MA]]
[[Category: charged p1 residue]]
[[Category: enzyme-inhibitor complex]]
 
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