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[[Image:2nxf.gif|left|200px]]


{{Structure
==Crystal Structure of a dimetal phosphatase from Danio rerio LOC 393393==
|PDB= 2nxf |SIZE=350|CAPTION= <scene name='initialview01'>2nxf</scene>, resolution 1.700&Aring;
<StructureSection load='2nxf' size='340' side='right'caption='[[2nxf]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> and <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>
<table><tr><td colspan='2'>[[2nxf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NXF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NXF FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
|GENE= Dr.12833, LOC 393393 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Danio rerio])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nxf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nxf OCA], [https://pdbe.org/2nxf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nxf RCSB], [https://www.ebi.ac.uk/pdbsum/2nxf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nxf ProSAT], [https://www.topsan.org/Proteins/CESG/2nxf TOPSAN]</span></td></tr>
 
</table>
'''Crystal Structure of a dimetal phosphatase from Danio rerio LOC 393393'''
== Function ==
 
[https://www.uniprot.org/uniprot/ADPRM_DANRE ADPRM_DANRE] Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose.
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2NXF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NXF OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nx/2nxf_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2nxf ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Danio rerio]]
[[Category: Danio rerio]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Bingman, C A.]]
[[Category: Bingman CA]]
[[Category: Bitto, E.]]
[[Category: Bitto E]]
[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
[[Category: McCoy JG]]
[[Category: Jr., G N.Phillips.]]
[[Category: Phillips Jr GN]]
[[Category: McCoy, J G.]]
[[Category: Wesenberg GE]]
[[Category: Wesenberg, G E.]]
[[Category: EOH]]
[[Category: PO4]]
[[Category: ZN]]
[[Category: center for eukaryotic structural genomic]]
[[Category: cesg]]
[[Category: dinuclear metal center phosphatase]]
[[Category: metallophosphoesterase]]
[[Category: metalloprotein]]
[[Category: protein structure initiative]]
[[Category: psi-2]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:52:31 2008''

Latest revision as of 00:11, 28 December 2023

Crystal Structure of a dimetal phosphatase from Danio rerio LOC 393393

2nxf, resolution 1.70Å

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