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==Solution structure of the KI O18/O8 Y87H immunoglobulin light chain variable domain==
==Solution structure of the KI O18/O8 Y87H immunoglobulin light chain variable domain==
<StructureSection load='2kqm' size='340' side='right' caption='[[2kqm]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2kqm' size='340' side='right'caption='[[2kqm]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2kqm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KQM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KQM FirstGlance]. <br>
<table><tr><td colspan='2'>[[2kqm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KQM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KQM FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2kqn|2kqn]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kqm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kqm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kqm RCSB], [http://www.ebi.ac.uk/pdbsum/2kqm PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kqm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kqm OCA], [https://pdbe.org/2kqm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kqm RCSB], [https://www.ebi.ac.uk/pdbsum/2kqm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kqm ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kq/2kqm_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kq/2kqm_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kqm ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2kqm" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Baden, E M]]
[[Category: Large Structures]]
[[Category: Peterson, F C]]
[[Category: Baden EM]]
[[Category: Ramirez-Alvarado, M]]
[[Category: Peterson FC]]
[[Category: Volkman, B F]]
[[Category: Ramirez-Alvarado M]]
[[Category: Amyloidosis]]
[[Category: Volkman BF]]
[[Category: Bence-jones protein]]
[[Category: Disulfide bond]]
[[Category: Homodimer]]
[[Category: Immune system]]
[[Category: Immunoglobulin domain]]
[[Category: Immunoglobulin kappa light chain]]
[[Category: Immunoglobulin v region]]

Latest revision as of 08:15, 30 October 2024

Solution structure of the KI O18/O8 Y87H immunoglobulin light chain variable domain

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