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==STRUCTURE OF A STREPTOCOCCUS MUTANS CE4 ESTERASE==
 
<StructureSection load='2w3z' size='340' side='right' caption='[[2w3z]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
==Structure of a Streptococcus mutans CE4 esterase==
<StructureSection load='2w3z' size='340' side='right'caption='[[2w3z]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2w3z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans_ua159 Streptococcus mutans ua159]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W3Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W3Z FirstGlance]. <br>
<table><tr><td colspan='2'>[[2w3z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_mutans_UA159 Streptococcus mutans UA159]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W3Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W3Z FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitin_deacetylase Chitin deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.41 3.5.1.41] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w3z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w3z RCSB], [http://www.ebi.ac.uk/pdbsum/2w3z PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w3z OCA], [https://pdbe.org/2w3z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w3z RCSB], [https://www.ebi.ac.uk/pdbsum/2w3z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w3z ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8DV82_STRMU Q8DV82_STRMU]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w3/2w3z_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w3/2w3z_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w3z ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2w3z" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Chitin deacetylase]]
[[Category: Large Structures]]
[[Category: Streptococcus mutans ua159]]
[[Category: Streptococcus mutans UA159]]
[[Category: Aalten, D M.F Van]]
[[Category: Crielaard W]]
[[Category: Cate, J M.Ten]]
[[Category: Deng DM]]
[[Category: Crielaard, W]]
[[Category: Rao VA]]
[[Category: Deng, D M]]
[[Category: Urch JE]]
[[Category: Rao, V A]]
[[Category: Ten Cate JM]]
[[Category: Urch, J E]]
[[Category: Van Aalten DMF]]
[[Category: Carbohydrate esterase family 4]]
[[Category: Cell surface surface deacetylase]]
[[Category: Divale metal cation dependent]]
[[Category: Glcnac de-n-acetylase]]
[[Category: Hydrolase]]
[[Category: Pgda]]