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==CRYSTAL STRUCTURE OF HUMAN PEROXISOMAL DELTA3,5, DELTA2,4-DIENOYL COA ISOMERASE==
 
<StructureSection load='2vre' size='340' side='right' caption='[[2vre]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
==crystal structure of human peroxisomal delta3,5,delta2,4-dienoyl coa isomerase==
<StructureSection load='2vre' size='340' side='right'caption='[[2vre]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2vre]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VRE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VRE FirstGlance]. <br>
<table><tr><td colspan='2'>[[2vre]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VRE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vre OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vre RCSB], [http://www.ebi.ac.uk/pdbsum/2vre PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vre OCA], [https://pdbe.org/2vre PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vre RCSB], [https://www.ebi.ac.uk/pdbsum/2vre PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vre ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ECH1_HUMAN ECH1_HUMAN] Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA.[UniProtKB:Q62651]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vr/2vre_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vr/2vre_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vre ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C]]
[[Category: Large Structures]]
[[Category: Bountra, C]]
[[Category: Arrowsmith C]]
[[Category: Delft, F Von]]
[[Category: Bountra C]]
[[Category: Edwards, A]]
[[Category: Edwards A]]
[[Category: Guo, K]]
[[Category: Guo K]]
[[Category: Kochan, G]]
[[Category: Kochan G]]
[[Category: Murray, J]]
[[Category: Murray J]]
[[Category: Oppermann, U]]
[[Category: Oppermann U]]
[[Category: Pilka, E]]
[[Category: Pilka E]]
[[Category: Roos, A]]
[[Category: Roos A]]
[[Category: Wikstrom, M]]
[[Category: Wikstrom M]]
[[Category: Yue, W]]
[[Category: Yue W]]
[[Category: 4-dienoyl-coa isomerase]]
[[Category: Von Delft F]]
[[Category: 5-delta2]]
[[Category: Delta3]]
[[Category: Fatty acid metabolism]]
[[Category: Isomerase]]
[[Category: Lipid metabolism]]
[[Category: Mitochondrion]]
[[Category: Peroxisome]]
[[Category: Phosphoprotein]]
[[Category: Transit peptide]]

Latest revision as of 15:29, 13 December 2023

crystal structure of human peroxisomal delta3,5,delta2,4-dienoyl coa isomerase

2vre, resolution 1.95Å

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