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==Crystal structure determination of a ternary complex of phospholipase A2 with a pentapeptide FLSYK and Ajmaline at 2.5 A resolution==
==Crystal structure determination of a ternary complex of phospholipase A2 with a pentapeptide FLSYK and Ajmaline at 2.5 A resolution==
<StructureSection load='3fg5' size='340' side='right' caption='[[3fg5]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='3fg5' size='340' side='right'caption='[[3fg5]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3fg5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Daboia_russellii_pulchella Daboia russellii pulchella]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FG5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FG5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3fg5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Daboia_russelii_pulchella Daboia russelii pulchella]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FG5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FG5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AJM:AJMALINE'>AJM</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zr8|1zr8]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AJM:AJMALINE'>AJM</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fg5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fg5 OCA], [https://pdbe.org/3fg5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fg5 RCSB], [https://www.ebi.ac.uk/pdbsum/3fg5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fg5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fg5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fg5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fg5 RCSB], [http://www.ebi.ac.uk/pdbsum/3fg5 PDBsum]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fg/3fg5_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fg/3fg5_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fg5 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Phospholipase A2|Phospholipase A2]]
*[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Daboia russellii pulchella]]
[[Category: Daboia russelii pulchella]]
[[Category: Bhushan, A]]
[[Category: Large Structures]]
[[Category: Kaur, P]]
[[Category: Bhushan A]]
[[Category: Kumar, M]]
[[Category: Kaur P]]
[[Category: Kumar, S]]
[[Category: Kumar M]]
[[Category: Sharma, S]]
[[Category: Kumar S]]
[[Category: Singh, N]]
[[Category: Sharma S]]
[[Category: Singh, T P]]
[[Category: Singh N]]
[[Category: Sinha, M]]
[[Category: Singh TP]]
[[Category: Srinivasan, A]]
[[Category: Sinha M]]
[[Category: Vikram, G]]
[[Category: Srinivasan A]]
[[Category: Ajmaline]]
[[Category: Vikram G]]
[[Category: Flsyk]]
[[Category: Hydrolase]]
[[Category: Pentapeptide]]
[[Category: Pla2]]
[[Category: Ternary complex]]
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