3h2b: Difference between revisions

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==Crystal structure of the SAM-dependent methyltransferase cg3271 from Corynebacterium glutamicum in complex with S-adenosyl-L-homocysteine and pyrophosphate. Northeast Structural Genomics Consortium Target CgR113A==
==Crystal structure of the SAM-dependent methyltransferase cg3271 from Corynebacterium glutamicum in complex with S-adenosyl-L-homocysteine and pyrophosphate. Northeast Structural Genomics Consortium Target CgR113A==
<StructureSection load='3h2b' size='340' side='right' caption='[[3h2b]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3h2b' size='340' side='right'caption='[[3h2b]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3h2b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Corynebacterium_glutamicum_atcc_13032 Corynebacterium glutamicum atcc 13032]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3H2B FirstGlance]. <br>
<table><tr><td colspan='2'>[[3h2b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynebacterium_glutamicum_ATCC_13032 Corynebacterium glutamicum ATCC 13032]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H2B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H2B FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cg3271 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=196627 Corynebacterium glutamicum ATCC 13032])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h2b OCA], [https://pdbe.org/3h2b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h2b RCSB], [https://www.ebi.ac.uk/pdbsum/3h2b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h2b ProSAT], [https://www.topsan.org/Proteins/NESGC/3h2b TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3h2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h2b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3h2b RCSB], [http://www.ebi.ac.uk/pdbsum/3h2b PDBsum], [http://www.topsan.org/Proteins/NESGC/3h2b TOPSAN]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h2/3h2b_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h2/3h2b_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h2b ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>


==See Also==
==See Also==
*[[SAM-dependent methyltransferase|SAM-dependent methyltransferase]]
*[[SAM-dependent methyltrasferase 3D structures|SAM-dependent methyltrasferase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Corynebacterium glutamicum atcc 13032]]
[[Category: Corynebacterium glutamicum ATCC 13032]]
[[Category: Acton, T B]]
[[Category: Large Structures]]
[[Category: Ciccosanti, C]]
[[Category: Acton TB]]
[[Category: Everett, J K]]
[[Category: Ciccosanti C]]
[[Category: Foote, E L]]
[[Category: Everett JK]]
[[Category: Forouhar, F]]
[[Category: Foote EL]]
[[Category: Hunt, J F]]
[[Category: Forouhar F]]
[[Category: Lew, S]]
[[Category: Hunt JF]]
[[Category: Montelione, G T]]
[[Category: Lew S]]
[[Category: Structural genomic]]
[[Category: Montelione GT]]
[[Category: Nair, R]]
[[Category: Nair R]]
[[Category: Rost, B]]
[[Category: Rost B]]
[[Category: Sahdev, S]]
[[Category: Sahdev S]]
[[Category: Seetharaman, J]]
[[Category: Seetharaman J]]
[[Category: Tong, L]]
[[Category: Tong L]]
[[Category: Wang, D]]
[[Category: Wang D]]
[[Category: Xiao, R]]
[[Category: Xiao R]]
[[Category: Alpha-beta protein]]
[[Category: Methyltransferase]]
[[Category: Nesg]]
[[Category: PSI, Protein structure initiative]]
[[Category: Transferase]]

Latest revision as of 06:16, 27 November 2024

Crystal structure of the SAM-dependent methyltransferase cg3271 from Corynebacterium glutamicum in complex with S-adenosyl-L-homocysteine and pyrophosphate. Northeast Structural Genomics Consortium Target CgR113A

3h2b, resolution 2.00Å

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