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[[Image:2ohd.jpg|left|200px]]


{{Structure
==Crystal structure of hypothetical molybdenum cofactor biosynthesis protein C from Sulfolobus tokodaii==
|PDB= 2ohd |SIZE=350|CAPTION= <scene name='initialview01'>2ohd</scene>, resolution 2.20&Aring;
<StructureSection load='2ohd' size='340' side='right'caption='[[2ohd]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2ohd]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii_str._7 Sulfurisphaera tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OHD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OHD FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
|GENE= ST0472 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=111955 Sulfolobus tokodaii])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ohd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ohd OCA], [https://pdbe.org/2ohd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ohd RCSB], [https://www.ebi.ac.uk/pdbsum/2ohd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ohd ProSAT]</span></td></tr>
}}
</table>
== Function ==
[https://www.uniprot.org/uniprot/MOAC_SULTO MOAC_SULTO] Together with MoaA, is involved in the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity).[HAMAP-Rule:MF_01224]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oh/2ohd_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ohd ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The crystal structure of a putative molybdenum-cofactor (Moco) biosynthesis protein C (MoaC) from Sulfolobus tokodaii (ST0472) was determined at 2.2 A resolution. The crystal belongs to the monoclinic space group C2, with unit-cell parameters a = 123.31, b = 78.58, c = 112.67 A, beta = 118.1 degrees . The structure was solved by molecular replacement using the structure of Escherichia coli MoaC as the probe model. The asymmetric unit is composed of a hexamer arranged as a trimer of dimers with noncrystallographic 32 symmetry. The structure of ST0472 is very similar to that of E. coli MoaC; however, in the ST0472 protein an additional loop formed by the insertion of seven residues participates in intermonomer interactions and the new structure also reveals the formation of an interdimer beta-sheet. These features may contribute to the stability of the oligomeric state.


'''Crystal structure of hypothetical molybdenum cofactor biosynthesis protein C from Sulfolobus tokodaii'''
Structure of a putative molybdenum-cofactor biosynthesis protein C (MoaC) from Sulfolobus tokodaii (ST0472).,Yoshida H, Yamada M, Kuramitsu S, Kamitori S Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Jul 1;64(Pt, 7):589-92. Epub 2008 Jun 11. PMID:18607082<ref>PMID:18607082</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
==About this Structure==
</div>
2OHD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii Sulfolobus tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OHD OCA].
<div class="pdbe-citations 2ohd" style="background-color:#fffaf0;"></div>
[[Category: Single protein]]
== References ==
[[Category: Sulfolobus tokodaii]]
<references/>
[[Category: Kamitori, S.]]
__TOC__
[[Category: Kuramitsu, S.]]
</StructureSection>
[[Category: Yamada, M.]]
[[Category: Large Structures]]
[[Category: Yoshida, H.]]
[[Category: Sulfurisphaera tokodaii str. 7]]
[[Category: alpha + beta]]
[[Category: Kamitori S]]
[[Category: biosynthetic protein]]
[[Category: Kuramitsu S]]
 
[[Category: Yamada M]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:59:44 2008''
[[Category: Yoshida H]]
Retrieved from "https://proteopedia.org/2ohd"