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==CRYSTAL STRUCTURE OF THE HUMAN RIBOSOMAL PROTEIN S6 KINASE==
 
<StructureSection load='2wnt' size='340' side='right' caption='[[2wnt]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
==Crystal Structure of the Human Ribosomal protein S6 kinase==
<StructureSection load='2wnt' size='340' side='right'caption='[[2wnt]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wnt]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WNT FirstGlance]. <br>
<table><tr><td colspan='2'>[[2wnt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WNT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wnt RCSB], [http://www.ebi.ac.uk/pdbsum/2wnt PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnt OCA], [https://pdbe.org/2wnt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wnt RCSB], [https://www.ebi.ac.uk/pdbsum/2wnt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wnt ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/2wnt_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/2wnt_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wnt ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Ribosomal protein S6 kinase|Ribosomal protein S6 kinase]]
*[[Ribosomal protein S6 kinase 3D structures|Ribosomal protein S6 kinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H]]
[[Category: Large Structures]]
[[Category: Bountra, C]]
[[Category: Arrowsmith CH]]
[[Category: Delft, F Von]]
[[Category: Bountra C]]
[[Category: Edwards, A]]
[[Category: Edwards A]]
[[Category: Elkins, J M]]
[[Category: Elkins JM]]
[[Category: King, O]]
[[Category: King O]]
[[Category: Knapp, S]]
[[Category: Knapp S]]
[[Category: Muniz, J R.C]]
[[Category: Muniz JRC]]
[[Category: Picaud, S]]
[[Category: Picaud S]]
[[Category: Salah, E]]
[[Category: Salah E]]
[[Category: Ugochukwu, E]]
[[Category: Ugochukwu E]]
[[Category: Wang, J]]
[[Category: Wang J]]
[[Category: Weigelt, J]]
[[Category: Weigelt J]]
[[Category: Atp-binding]]
[[Category: Von Delft F]]
[[Category: Human]]
[[Category: Kinase]]
[[Category: Magnesium]]
[[Category: Metal-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Ribosomal]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]

Latest revision as of 01:29, 21 November 2024

Crystal Structure of the Human Ribosomal protein S6 kinase

2wnt, resolution 2.40Å

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