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[[Image:2opx.gif|left|200px]]


{{Structure
==Crystal Structure of Lactaldehyde Dehydrogenase from Escherichia coli==
|PDB= 2opx |SIZE=350|CAPTION= <scene name='initialview01'>2opx</scene>, resolution 2.530&Aring;
<StructureSection load='2opx' size='340' side='right'caption='[[2opx]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=DXC:(3ALPHA,5ALPHA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID'>DXC</scene>
<table><tr><td colspan='2'>[[2opx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21(DE3) Escherichia coli BL21(DE3)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OPX FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Lactaldehyde_dehydrogenase Lactaldehyde dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.22 1.2.1.22]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.53&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DXC:(3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC+ACID'>DXC</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2opx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2opx OCA], [https://pdbe.org/2opx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2opx RCSB], [https://www.ebi.ac.uk/pdbsum/2opx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2opx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ALDA_ECOLI ALDA_ECOLI] Acts on lactaldehyde as well as other aldehydes.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/op/2opx_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2opx ConSurf].
<div style="clear:both"></div>


'''Crystal Structure of Lactaldehyde Dehydrogenase from Escherichia coli'''
==See Also==
 
*[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2OPX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPX OCA].
[[Category: Large Structures]]
[[Category: Escherichia coli]]
[[Category: Francuski D]]
[[Category: Lactaldehyde dehydrogenase]]
[[Category: Rossocha M]]
[[Category: Single protein]]
[[Category: Saenger W]]
[[Category: Francuski, D.]]
[[Category: Rossocha, M.]]
[[Category: Saenger, W.]]
[[Category: DXC]]
[[Category: rossmann fold; dehydrogenase; deoxycholate; protein detergent complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:02:57 2008''

Latest revision as of 00:21, 28 December 2023

Crystal Structure of Lactaldehyde Dehydrogenase from Escherichia coli

2opx, resolution 2.53Å

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