2oqk: Difference between revisions
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==Crystal structure of putative Cryptosporidium parvum translation initiation factor eIF-1A== | |||
<StructureSection load='2oqk' size='340' side='right'caption='[[2oqk]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
| | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2oqk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OQK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OQK FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oqk OCA], [https://pdbe.org/2oqk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oqk RCSB], [https://www.ebi.ac.uk/pdbsum/2oqk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oqk ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/Q5CVP1_CRYPI Q5CVP1_CRYPI] Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.[RuleBase:RU004365] | |||
== Evolutionary Conservation == | |||
== | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | |||
[[Category: Cryptosporidium parvum]] | <jmolCheckbox> | ||
[[Category: | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oq/2oqk_consurf.spt"</scriptWhenChecked> | ||
[[Category: Altamentova | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
[[Category: Arrowsmith | <text>to colour the structure by Evolutionary Conservation</text> | ||
[[Category: Bochkarev | </jmolCheckbox> | ||
[[Category: Brokx | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2oqk ConSurf]. | ||
[[Category: Dong | <div style="clear:both"></div> | ||
[[Category: Edwards | __TOC__ | ||
[[Category: Hassanali | </StructureSection> | ||
[[Category: Hui | [[Category: Cryptosporidium parvum Iowa II]] | ||
[[Category: Kozieradzki | [[Category: Large Structures]] | ||
[[Category: Lew | [[Category: Altamentova S]] | ||
[[Category: Lin | [[Category: Arrowsmith CH]] | ||
[[Category: Qiu | [[Category: Bochkarev A]] | ||
[[Category: Brokx SJ]] | |||
[[Category: Sundstrom | [[Category: Dong A]] | ||
[[Category: Vedadi | [[Category: Edwards AM]] | ||
[[Category: Wasney | [[Category: Hassanali A]] | ||
[[Category: Weigelt | [[Category: Hui R]] | ||
[[Category: Zhao | [[Category: Kozieradzki I]] | ||
[[Category: Lew J]] | |||
[[Category: Lin L]] | |||
[[Category: Qiu W]] | |||
[[Category: Sundstrom M]] | |||
[[Category: Vedadi M]] | |||
[[Category: Wasney G]] | |||
[[Category: Weigelt J]] | |||
[[Category: Zhao Y]] | |||
Latest revision as of 01:17, 21 November 2024
Crystal structure of putative Cryptosporidium parvum translation initiation factor eIF-1A
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