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==The crystal structure of one domain of the PTS system, IIabc component from Clostridium difficile==
==The crystal structure of one domain of the PTS system, IIabc component from Clostridium difficile==
<StructureSection load='3ipj' size='340' side='right' caption='[[3ipj]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
<StructureSection load='3ipj' size='340' side='right'caption='[[3ipj]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ipj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_difficile_630 Clostridium difficile 630]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IPJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IPJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ipj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridioides_difficile_630 Clostridioides difficile 630]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IPJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IPJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD0469, GI:115249482 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272563 Clostridium difficile 630])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ipj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ipj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ipj RCSB], [http://www.ebi.ac.uk/pdbsum/3ipj PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ipj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ipj OCA], [https://pdbe.org/3ipj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ipj RCSB], [https://www.ebi.ac.uk/pdbsum/3ipj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ipj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q188R0_CLOD6 Q188R0_CLOD6]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ip/3ipj_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ip/3ipj_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ipj ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Phosphotransferase|Phosphotransferase]]
*[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Clostridium difficile 630]]
[[Category: Clostridioides difficile 630]]
[[Category: Bigelow, L]]
[[Category: Large Structures]]
[[Category: Cobb, G]]
[[Category: Bigelow L]]
[[Category: Joachimiak, A]]
[[Category: Cobb G]]
[[Category: Structural genomic]]
[[Category: Joachimiak A]]
[[Category: Zhang, R]]
[[Category: Zhang R]]
[[Category: Cell membrane]]
[[Category: Iiabc component]]
[[Category: Kinase]]
[[Category: Mcsg]]
[[Category: Membrane]]
[[Category: Phosphotransferase system]]
[[Category: PSI, Protein structure initiative]]
[[Category: Pts system]]
[[Category: Sugar transport]]
[[Category: Transferase]]
[[Category: Transmembrane]]
[[Category: Transport]]