2os3: Difference between revisions
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==Structures of actinonin bound peptide deformylases from E. faecalis and S. pyogenes== | |||
<StructureSection load='2os3' size='340' side='right'caption='[[2os3]], [[Resolution|resolution]] 2.26Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2os3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes_M1_GAS Streptococcus pyogenes M1 GAS]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OS3 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.26Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB2:ACTINONIN'>BB2</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2os3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2os3 OCA], [https://pdbe.org/2os3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2os3 RCSB], [https://www.ebi.ac.uk/pdbsum/2os3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2os3 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DEF_STRP1 DEF_STRP1] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity). | |||
== Evolutionary Conservation == | |||
== | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | |||
<jmolCheckbox> | |||
[[Category: | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/os/2os3_consurf.spt"</scriptWhenChecked> | ||
[[Category: Streptococcus pyogenes]] | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
[[Category: Choi | <text>to colour the structure by Evolutionary Conservation</text> | ||
[[Category: Kim | </jmolCheckbox> | ||
[[Category: Kim | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2os3 ConSurf]. | ||
[[Category: Lee | <div style="clear:both"></div> | ||
[[Category: Moon | __TOC__ | ||
[[Category: Parh | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Streptococcus pyogenes M1 GAS]] | |||
[[Category: Choi K]] | |||
[[Category: Kim EE]] | |||
[[Category: Kim K-H]] | |||
[[Category: Lee HK]] | |||
[[Category: Moon JH]] | |||
[[Category: Parh HS]] | |||
Latest revision as of 08:58, 25 October 2023
Structures of actinonin bound peptide deformylases from E. faecalis and S. pyogenes
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