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==Crystal structure of human primase==
==Crystal structure of human primase==
<StructureSection load='4rr2' size='340' side='right' caption='[[4rr2]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
<StructureSection load='4rr2' size='340' side='right'caption='[[4rr2]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4rr2]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RR2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4rr2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RR2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rr2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rr2 RCSB], [http://www.ebi.ac.uk/pdbsum/4rr2 PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rr2 OCA], [https://pdbe.org/4rr2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rr2 RCSB], [https://www.ebi.ac.uk/pdbsum/4rr2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rr2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PRI1_HUMAN PRI1_HUMAN]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. [[http://www.uniprot.org/uniprot/PRI2_HUMAN PRI2_HUMAN]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.  
[https://www.uniprot.org/uniprot/PRI1_HUMAN PRI1_HUMAN] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4rr2" style="background-color:#fffaf0;"></div>
==See Also==
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Babayeva, N D]]
[[Category: Homo sapiens]]
[[Category: Baranovskiy, A G]]
[[Category: Large Structures]]
[[Category: Gu, J]]
[[Category: Babayeva ND]]
[[Category: Suwa, Y]]
[[Category: Baranovskiy AG]]
[[Category: Tahirov, T H]]
[[Category: Gu J]]
[[Category: Dna replication]]
[[Category: Suwa Y]]
[[Category: Dna-binding]]
[[Category: Tahirov TH]]
[[Category: Dna-directed rna polymerase]]
[[Category: Iron-sulfur cluster]]
[[Category: Metal-binding]]
[[Category: Nucleotidyltransferase]]
[[Category: Phosphoprotein]]
[[Category: Pol alpha]]
[[Category: Polymerase]]
[[Category: Primase]]
[[Category: Primosome]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/4rr2"