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==SPLA SERINE PROTEASE OF STAPHYLOCOCCUS AUREUS (2.4A)==
 
<StructureSection load='2w7u' size='340' side='right' caption='[[2w7u]], [[Resolution|resolution]] 2.43&Aring;' scene=''>
==SplA serine protease of Staphylococcus aureus (2.4A)==
<StructureSection load='2w7u' size='340' side='right'caption='[[2w7u]], [[Resolution|resolution]] 2.43&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2w7u]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W7U FirstGlance]. <br>
<table><tr><td colspan='2'>[[2w7u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W7U FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2w7s|2w7s]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.43&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamyl_endopeptidase Glutamyl endopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.19 3.4.21.19] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w7u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7u OCA], [https://pdbe.org/2w7u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w7u RCSB], [https://www.ebi.ac.uk/pdbsum/2w7u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w7u ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w7u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w7u RCSB], [http://www.ebi.ac.uk/pdbsum/2w7u PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SPLA_STAA8 SPLA_STAA8]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w7/2w7u_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w7/2w7u_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w7u ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2w7u" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Glutamyl endopeptidase]]
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Bista, M]]
[[Category: Bista M]]
[[Category: Boulware, K T]]
[[Category: Boulware KT]]
[[Category: Daugherty, P S]]
[[Category: Daugherty PS]]
[[Category: Dubin, A]]
[[Category: Dubin A]]
[[Category: Dubin, G]]
[[Category: Dubin G]]
[[Category: Enghild, J J]]
[[Category: Enghild JJ]]
[[Category: Kisielewska, M]]
[[Category: Kisielewska M]]
[[Category: Popowicz, G M]]
[[Category: Popowicz GM]]
[[Category: Potempa, J]]
[[Category: Potempa J]]
[[Category: Pustelny, K]]
[[Category: Pustelny K]]
[[Category: Stec-Niemczyka, J]]
[[Category: Stec-Niemczyka J]]
[[Category: Stennicke, H R]]
[[Category: Stennicke HR]]
[[Category: Thogersen, I B]]
[[Category: Thogersen IB]]
[[Category: Family s1]]
[[Category: Hydrolase]]

Latest revision as of 15:47, 13 December 2023

SplA serine protease of Staphylococcus aureus (2.4A)

2w7u, resolution 2.43Å

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