2pa6: Difference between revisions

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[[Image:2pa6.jpg|left|200px]]


{{Structure
==Crystal structure of MJ0232 from Methanococcus jannaschii==
|PDB= 2pa6 |SIZE=350|CAPTION= <scene name='initialview01'>2pa6</scene>, resolution 1.85&Aring;
<StructureSection load='2pa6' size='340' side='right'caption='[[2pa6]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2pa6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PA6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PA6 FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
|GENE= eno ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 Methanocaldococcus jannaschii])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pa6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pa6 OCA], [https://pdbe.org/2pa6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pa6 RCSB], [https://www.ebi.ac.uk/pdbsum/2pa6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pa6 ProSAT], [https://www.topsan.org/Proteins/RSGI/2pa6 TOPSAN]</span></td></tr>
}}
</table>
== Function ==
[https://www.uniprot.org/uniprot/ENO_METJA ENO_METJA] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pa/2pa6_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pa6 ConSurf].
<div style="clear:both"></div>


'''Crystal structure of MJ0232 from Methanococcus jannaschii'''
==See Also==
 
*[[Enolase 3D structures|Enolase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2PA6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PA6 OCA].
[[Category: Large Structures]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Phosphopyruvate hydratase]]
[[Category: Kunishima N]]
[[Category: Single protein]]
[[Category: Yamamoto H]]
[[Category: Kunishima, N.]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Yamamoto, H.]]
[[Category: glycolysis]]
[[Category: lyase]]
[[Category: magnesium]]
[[Category: metal-binding]]
[[Category: national project on protein and functional analyse]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
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