4y0l: Difference between revisions
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==Mycobacterial membrane protein MmpL11D2== | |||
<StructureSection load='4y0l' size='340' side='right'caption='[[4y0l]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4y0l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y0L FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
[[Category: Torres | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y0l OCA], [https://pdbe.org/4y0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y0l RCSB], [https://www.ebi.ac.uk/pdbsum/4y0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y0l ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MMPLB_MYCTU MMPLB_MYCTU] Part of a heme-iron acquisition system. Receives heme from the heme-binding protein Rv0203 and transports it into the mycobacterial cell. Contributes to virulence.<ref>PMID:15908378</ref> <ref>PMID:21383189</ref> <ref>PMID:23760277</ref> Could also transport the mycolic acid-containing lipids monomeromycolyl diacylglycerol (MMDAG) and mycolate ester wax (WE) to the bacterial surface.<ref>PMID:23836904</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis H37Rv]] | |||
[[Category: Chim N]] | |||
[[Category: Goulding CW]] | |||
[[Category: Torres R]] | |||
Latest revision as of 13:02, 1 March 2024
Mycobacterial membrane protein MmpL11D2
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