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==Crystal structure of C. violaceum phenylalanine hydroxylase D139E mutation==
==Crystal structure of C. violaceum phenylalanine hydroxylase D139E mutation==
<StructureSection load='4q3w' size='340' side='right' caption='[[4q3w]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
<StructureSection load='4q3w' size='340' side='right'caption='[[4q3w]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4q3w]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q3W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q3W FirstGlance]. <br>
<table><tr><td colspan='2'>[[4q3w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chromobacterium_violaceum_ATCC_12472 Chromobacterium violaceum ATCC 12472]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q3W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q3W FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tk4|3tk4]], [[1ltv|1ltv]], [[4q3x|4q3x]], [[4q3y|4q3y]], [[4q3z|4q3z]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q3w OCA], [https://pdbe.org/4q3w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q3w RCSB], [https://www.ebi.ac.uk/pdbsum/4q3w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q3w ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q3w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q3w RCSB], [http://www.ebi.ac.uk/pdbsum/4q3w PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PH4H_CHRVO PH4H_CHRVO]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4q3w" style="background-color:#fffaf0;"></div>
==See Also==
*[[Hydroxylases 3D structures|Hydroxylases 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Phenylalanine 4-monooxygenase]]
[[Category: Chromobacterium violaceum ATCC 12472]]
[[Category: Abu-Omar, M M]]
[[Category: Large Structures]]
[[Category: Das, C]]
[[Category: Abu-Omar MM]]
[[Category: Ronau, J A]]
[[Category: Das C]]
[[Category: Biopterin]]
[[Category: Ronau JA]]
[[Category: Chromobacterium]]
[[Category: Hydroxylase]]
[[Category: Kinetic]]
[[Category: Metal]]
[[Category: Mixed alpha helix-beta sheet]]
[[Category: Mutation]]
[[Category: Oxidoreductase]]
[[Category: Phenylalanine hydroxylase]]
[[Category: Phenylketonuria]]
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