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==Crystal structure of unliganded CH59UA, the inferred unmutated ancestor of the RV144 anti-HIV antibody lineage producing CH59==
==Crystal structure of unliganded CH59UA, the inferred unmutated ancestor of the RV144 anti-HIV antibody lineage producing CH59==
<StructureSection load='4qf1' size='340' side='right' caption='[[4qf1]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='4qf1' size='340' side='right'caption='[[4qf1]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4qf1]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QF1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QF1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4qf1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QF1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QF1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4hpy|4hpy]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qf1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qf1 RCSB], [http://www.ebi.ac.uk/pdbsum/4qf1 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qf1 OCA], [https://pdbe.org/4qf1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qf1 RCSB], [https://www.ebi.ac.uk/pdbsum/4qf1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qf1 ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4qf1" style="background-color:#fffaf0;"></div>
==See Also==
*[[Antibody 3D structures|Antibody 3D structures]]
*[[Sandbox 20009|Sandbox 20009]]
*[[3D structures of human antibody|3D structures of human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Alam, S M]]
[[Category: Homo sapiens]]
[[Category: Bonsignori, M]]
[[Category: Large Structures]]
[[Category: Bradley, T]]
[[Category: Alam SM]]
[[Category: Dennison, S M]]
[[Category: Bonsignori M]]
[[Category: Easterhoff, D]]
[[Category: Bradley T]]
[[Category: Haynes, B F]]
[[Category: Dennison SM]]
[[Category: Jaeger, F H]]
[[Category: Easterhoff D]]
[[Category: Kaewkungwal, J]]
[[Category: Haynes BF]]
[[Category: Kelsoe, G]]
[[Category: Jaeger FH]]
[[Category: Kepler, T B]]
[[Category: Kaewkungwal J]]
[[Category: Kim, J]]
[[Category: Kelsoe G]]
[[Category: Liao, H X]]
[[Category: Kepler TB]]
[[Category: Lloyd, K E]]
[[Category: Kim J]]
[[Category: Luo, K]]
[[Category: Liao H-X]]
[[Category: Michael, N]]
[[Category: Lloyd KE]]
[[Category: Montefiori, D C]]
[[Category: Luo K]]
[[Category: Moody, M A]]
[[Category: Michael N]]
[[Category: Morris, L]]
[[Category: Montefiori DC]]
[[Category: Nicely, N I]]
[[Category: Moody MA]]
[[Category: Nitayaphan, S]]
[[Category: Morris L]]
[[Category: Parks, R]]
[[Category: Nicely NI]]
[[Category: Pitisuttithum, P]]
[[Category: Nitayaphan S]]
[[Category: Rerks-Ngarm, S]]
[[Category: Parks R]]
[[Category: Santra, S]]
[[Category: Pitisuttithum P]]
[[Category: Scearce, R M]]
[[Category: Rerks-Ngarm S]]
[[Category: Stolarchuk, C]]
[[Category: Santra S]]
[[Category: Sutherland, L L]]
[[Category: Scearce RM]]
[[Category: Tomaras, G]]
[[Category: Stolarchuk C]]
[[Category: Wiehe, K]]
[[Category: Sutherland LL]]
[[Category: Zhang, R]]
[[Category: Tomaras G]]
[[Category: Anti-hiv antibody]]
[[Category: Wiehe K]]
[[Category: Gp120]]
[[Category: Zhang R]]
[[Category: Immune system]]