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==Crystal Structure of C.elegans Thymidylate Synthase in complex with an inhibitor N(4)OHdCMP==
==Crystal Structure of C.elegans Thymidylate Synthase in complex with an inhibitor N(4)OHdCMP==
<StructureSection load='4psg' size='340' side='right' caption='[[4psg]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='4psg' size='340' side='right'caption='[[4psg]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4psg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PSG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PSG FirstGlance]. <br>
<table><tr><td colspan='2'>[[4psg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PSG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PSG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NOH:2-DEOXY-N-HYDROXYCYTIDINE+5-(DIHYDROGEN+PHOSPHATE)'>NOH</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4iqb|4iqb]], [[4irr|4irr]], [[4iqq|4iqq]], [[4g9u|4g9u]], [[4ein|4ein]], [[4ez8|4ez8]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NOH:2-DEOXY-N-HYDROXYCYTIDINE+5-(DIHYDROGEN+PHOSPHATE)'>NOH</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4psg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4psg OCA], [https://pdbe.org/4psg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4psg RCSB], [https://www.ebi.ac.uk/pdbsum/4psg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4psg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4psg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4psg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4psg RCSB], [http://www.ebi.ac.uk/pdbsum/4psg PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9Y052_CAEEL Q9Y052_CAEEL]
==See Also==
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Thymidylate synthase]]
[[Category: Caenorhabditis elegans]]
[[Category: Jarmula, A]]
[[Category: Large Structures]]
[[Category: Rode, W]]
[[Category: Jarmula A]]
[[Category: Wilk, P]]
[[Category: Rode W]]
[[Category: Enzyme]]
[[Category: Wilk P]]
[[Category: Methyltransferase]]
[[Category: Nucleotide biosynthesis]]
[[Category: Protein dimer]]
[[Category: Transferase]]
[[Category: Transferase-transferase inhibitor complex]]
Retrieved from "https://proteopedia.org/4psg"