4qrh: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
(3 intermediate revisions by the same user not shown)
Line 1: Line 1:
==Molecular mechanism and evolution of guanylate kinase regulation by (p)ppGpp==
==Molecular mechanism and evolution of guanylate kinase regulation by (p)ppGpp==
<StructureSection load='4qrh' size='340' side='right' caption='[[4qrh]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='4qrh' size='340' side='right'caption='[[4qrh]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4qrh]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QRH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QRH FirstGlance]. <br>
<table><tr><td colspan='2'>[[4qrh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_USA300-ISMMS1 Staphylococcus aureus USA300-ISMMS1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QRH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QRH FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0O2:GUANOSINE+5-(TETRAHYDROGEN+TRIPHOSPHATE)+3-(TRIHYDROGEN+DIPHOSPHATE)'>0O2</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2j41|2j41]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0O2:GUANOSINE+5-(TETRAHYDROGEN+TRIPHOSPHATE)+3-(TRIHYDROGEN+DIPHOSPHATE)'>0O2</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Guanylate_kinase Guanylate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.8 2.7.4.8] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qrh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qrh OCA], [https://pdbe.org/4qrh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qrh RCSB], [https://www.ebi.ac.uk/pdbsum/4qrh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qrh ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qrh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qrh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qrh RCSB], [http://www.ebi.ac.uk/pdbsum/4qrh PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/W6E076_STAAU W6E076_STAAU]] Essential for recycling GMP and indirectly, cGMP.[HAMAP-Rule:MF_00328][SAAS:SAAS00152809]  
[https://www.uniprot.org/uniprot/A0A0J9X1Z9_STAAU A0A0J9X1Z9_STAAU]  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 18: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4qrh" style="background-color:#fffaf0;"></div>
==See Also==
*[[Guanylate kinase 3D structures|Guanylate kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Guanylate kinase]]
[[Category: Large Structures]]
[[Category: Keck, J L]]
[[Category: Staphylococcus aureus USA300-ISMMS1]]
[[Category: Krasny, K]]
[[Category: Keck JL]]
[[Category: Liu, K]]
[[Category: Krasny K]]
[[Category: Myers, A R]]
[[Category: Liu K]]
[[Category: Satyshur, K A]]
[[Category: Myers AR]]
[[Category: Wnag, J D]]
[[Category: Satyshur KA]]
[[Category: Phosphotransferase]]
[[Category: Wnag JD]]
[[Category: Pppgpp]]
[[Category: Transferase]]

Latest revision as of 17:35, 20 September 2023

Molecular mechanism and evolution of guanylate kinase regulation by (p)ppGpp

4qrh, resolution 1.65Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA