4yk5: Difference between revisions

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New page: '''Unreleased structure''' The entry 4yk5 is ON HOLD Authors: Luz, J.G., Antonysamy, S., Kuklish, S.L., Fisher, M.J. Description: Crystal Structures of mPGES-1 Inhibitor Complexes [[Ca...
 
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'''Unreleased structure'''


The entry 4yk5 is ON HOLD
==Crystal Structures of mPGES-1 Inhibitor Complexes==
<StructureSection load='4yk5' size='340' side='right'caption='[[4yk5]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4yk5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YK5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YK5 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.42&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4DV:3-[1-(4-CHLOROBENZYL)-5-(2-FLUORO-2-METHYLBIPHENYL-4-YL)-3-METHYL-1H-INDOL-2-YL]-2,2-DIMETHYLPROPANOIC+ACID'>4DV</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=JZR:HEXYL+BETA-D-GLUCOPYRANOSIDE'>JZR</scene>, <scene name='pdbligand=PG0:2-(2-METHOXYETHOXY)ETHANOL'>PG0</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yk5 OCA], [https://pdbe.org/4yk5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yk5 RCSB], [https://www.ebi.ac.uk/pdbsum/4yk5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yk5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PTGES_HUMAN PTGES_HUMAN] Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).<ref>PMID:18682561</ref>


Authors: Luz, J.G., Antonysamy, S., Kuklish, S.L., Fisher, M.J.
==See Also==
 
*[[Prostaglandin E synthase|Prostaglandin E synthase]]
Description: Crystal Structures of mPGES-1 Inhibitor Complexes
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Luz, J.G]]
__TOC__
[[Category: Fisher, M.J]]
</StructureSection>
[[Category: Kuklish, S.L]]
[[Category: Homo sapiens]]
[[Category: Antonysamy, S]]
[[Category: Large Structures]]
[[Category: Antonysamy S]]
[[Category: Fisher MJ]]
[[Category: Kuklish SL]]
[[Category: Luz JG]]
Retrieved from "https://proteopedia.org/4yk5"