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==Crystal structure of MltF from Pseudomonas aeruginosa complexed with isoleucine==
==Crystal structure of MltF from Pseudomonas aeruginosa complexed with isoleucine==
<StructureSection load='4oz9' size='340' side='right' caption='[[4oz9]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
<StructureSection load='4oz9' size='340' side='right'caption='[[4oz9]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4oz9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OZ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OZ9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4oz9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OZ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OZ9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ILE:ISOLEUCINE'>ILE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.24&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oz9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4oz9 RCSB], [http://www.ebi.ac.uk/pdbsum/4oz9 PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ILE:ISOLEUCINE'>ILE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4oz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oz9 OCA], [https://pdbe.org/4oz9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4oz9 RCSB], [https://www.ebi.ac.uk/pdbsum/4oz9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4oz9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MLTF_PSEAE MLTF_PSEAE]] Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.[HAMAP-Rule:MF_02016]  
[https://www.uniprot.org/uniprot/MLTF_PSEAE MLTF_PSEAE] Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.[HAMAP-Rule:MF_02016]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Reddem, E]]
[[Category: Large Structures]]
[[Category: Thunnissen, A M.W H]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Abc substrate binding-like domain]]
[[Category: Reddem E]]
[[Category: Glycosyltransferase]]
[[Category: Thunnissen AMWH]]
[[Category: Lytic transglycosylase]]
[[Category: Peptidoglycan]]

Latest revision as of 00:38, 28 December 2023

Crystal structure of MltF from Pseudomonas aeruginosa complexed with isoleucine

4oz9, resolution 2.24Å

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