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[[Image:2r6z.jpg|left|200px]]


{{Structure
==Crystal structure of the SAM-dependent methyltransferase NGO1261 from Neisseria gonorrhoeae, Northeast Structural Genomics Consortium Target NgR48==
|PDB= 2r6z |SIZE=350|CAPTION= <scene name='initialview01'>2r6z</scene>, resolution 1.80&Aring;
<StructureSection load='2r6z' size='340' side='right'caption='[[2r6z]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2r6z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"diplococcus_gonorrhoeae"_(zopf_1885)_lehmann_and_neumann_1896 "diplococcus gonorrhoeae" (zopf 1885) lehmann and neumann 1896]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R6Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R6Z FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
|GENE= NGO1261 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=485 Neisseria gonorrhoeae])
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NGO1261 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=485 "Diplococcus gonorrhoeae" (Zopf 1885) Lehmann and Neumann 1896])</td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r6z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r6z OCA], [https://pdbe.org/2r6z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r6z RCSB], [https://www.ebi.ac.uk/pdbsum/2r6z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r6z ProSAT], [https://www.topsan.org/Proteins/NESGC/2r6z TOPSAN]</span></td></tr>
 
</table>
'''Crystal structure of the SAM-dependent methyltransferase NGO1261 from Neisseria gonorrhoeae, Northeast Structural Genomics Consortium Target NgR48'''
== Function ==
 
[[https://www.uniprot.org/uniprot/RSMJ_NEIGO RSMJ_NEIGO]] Specifically methylates the guanosine in position 1516 of 16S rRNA.[HAMAP-Rule:MF_01523]
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2R6Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Neisseria_gonorrhoeae Neisseria gonorrhoeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R6Z OCA].  
Check<jmol>
[[Category: Neisseria gonorrhoeae]]
  <jmolCheckbox>
[[Category: Single protein]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r6/2r6z_consurf.spt"</scriptWhenChecked>
[[Category: Abashidze, M.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Acton, T B.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Baran, M C.]]
  </jmolCheckbox>
[[Category: Fang, Y.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r6z ConSurf].
[[Category: Forouhar, F.]]
<div style="clear:both"></div>
[[Category: Hunt, J F.]]
__TOC__
[[Category: Mao, L.]]
</StructureSection>
[[Category: Montelione, G T.]]
[[Category: Large Structures]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Abashidze, M]]
[[Category: Nwosu, C.]]
[[Category: Acton, T B]]
[[Category: Seetharaman, J.]]
[[Category: Baran, M C]]
[[Category: Tong, L.]]
[[Category: Fang, Y]]
[[Category: Xiao, R.]]
[[Category: Forouhar, F]]
[[Category: alpha-beta protein]]
[[Category: Hunt, J F]]
[[Category: nesg]]
[[Category: Mao, L]]
[[Category: northeast structural genomics consortium]]
[[Category: Montelione, G T]]
[[Category: protein structure initiative]]
[[Category: Structural genomic]]
[[Category: psi-2]]
[[Category: Nwosu, C]]
[[Category: structural genomic]]
[[Category: Seetharaman, J]]
[[Category: transferase]]
[[Category: Tong, L]]
 
[[Category: Xiao, R]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:33:11 2008''
[[Category: Alpha-beta protein]]
[[Category: Nesg]]
[[Category: PSI, Protein structure initiative]]
[[Category: Transferase]]