2rfq: Difference between revisions

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[[Image:2rfq.gif|left|200px]]


{{Structure
==Crystal structure of 3-HSA hydroxylase from Rhodococcus sp. RHA1==
|PDB= 2rfq |SIZE=350|CAPTION= <scene name='initialview01'>2rfq</scene>, resolution 1.65&Aring;
<StructureSection load='2rfq' size='340' side='right'caption='[[2rfq]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=1PS:3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE'>1PS</scene>
<table><tr><td colspan='2'>[[2rfq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhojr Rhojr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RFQ FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PS:3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE'>1PS</scene></td></tr>
|GENE= hsaA, RHA1_ro04539 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=101510 Rhodococcus sp. RHA1])
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
}}
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hsaA, RHA1_ro04539 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=101510 RHOJR])</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rfq OCA], [https://pdbe.org/2rfq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rfq RCSB], [https://www.ebi.ac.uk/pdbsum/2rfq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rfq ProSAT], [https://www.topsan.org/Proteins/MCSG/2rfq TOPSAN]</span></td></tr>
'''Crystal structure of 3-HSA hydroxylase from Rhodococcus sp. RHA1'''
</table>
 
== Function ==
 
[[https://www.uniprot.org/uniprot/HSAA_RHOSR HSAA_RHOSR]] Catalyzes the o-hydroxylation of 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione (3-HSA) to 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione (3,4-DHSA) in the catabolism of cholesterol.<ref>PMID:17264217</ref> 
==About this Structure==
== Evolutionary Conservation ==
2RFQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp._rha1 Rhodococcus sp. rha1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFQ OCA].  
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rf/2rfq_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rfq ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rhojr]]
[[Category: Chang, C]]
[[Category: Edwards, A M]]
[[Category: Joachimiak, A]]
[[Category: Kagan, O]]
[[Category: Structural genomic]]
[[Category: Savchenko, A]]
[[Category: Skarina, T]]
[[Category: 3-hsa hydroxylase]]
[[Category: Mcsg]]
[[Category: Oxidoreductase]]
[[Category: PSI, Protein structure initiative]]
[[Category: Rhodococcus sp. rha1]]
[[Category: Rhodococcus sp. rha1]]
[[Category: Single protein]]
[[Category: Chang, C.]]
[[Category: Edwards, A M.]]
[[Category: Joachimiak, A.]]
[[Category: Kagan, O.]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Savchenko, A.]]
[[Category: Skarina, T.]]
[[Category: 1PS]]
[[Category: 3-hsa hydroxylase]]
[[Category: mcsg]]
[[Category: midwest center for structural genomic]]
[[Category: oxidoreductase]]
[[Category: protein structure initiative]]
[[Category: psi-2]]
[[Category: rhodococcus sp. rha1]]
[[Category: structural genomic]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:35:40 2008''
Retrieved from "https://proteopedia.org/2rfq"