4yw7: Difference between revisions
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New page: '''Unreleased structure''' The entry 4yw7 is ON HOLD until Mar 20 2017 Authors: Visini, R., Jin, X., Michaud, G., Bergmann, M., Gillon, E., Imberty, A., Stocker, A., Darbre, T., Pieters... |
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==Structural Insight into Divalent Galactoside Binding to Pseudomonas aeruginosa lectin LecA== | |||
<StructureSection load='4yw7' size='340' side='right'caption='[[4yw7]], [[Resolution|resolution]] 1.82Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4yw7]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YW7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YW7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4J0:(2R,3R,4S,5R,6R,2R,3R,4S,5R,6R)-2,2-([(2R,3R,4S,5S,6S)-3,4-DIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-2,5-DIYL]BIS{1H-1,2,3-TRIAZOLE-1,4-DIYL[(2S,3R,4S,5S,6S)-3,4-DIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-2,5-DIYL]-1H-1,2,3-TRIAZOLE-1,4-DIYLPROPANE-3,1-DIYLOXY})BIS[6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL]'>4J0</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yw7 OCA], [https://pdbe.org/4yw7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yw7 RCSB], [https://www.ebi.ac.uk/pdbsum/4yw7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yw7 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PA1L_PSEAE PA1L_PSEAE] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity. | |||
==See Also== | |||
*[[Galactose-binding lectin|Galactose-binding lectin]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Pseudomonas aeruginosa]] | ||
[[Category: Gillon | [[Category: Bergmann M]] | ||
[[Category: | [[Category: Darbre T]] | ||
[[Category: | [[Category: Gillon E]] | ||
[[Category: | [[Category: Imberty A]] | ||
[[Category: | [[Category: Jin X]] | ||
[[Category: | [[Category: Michaud G]] | ||
[[Category: Stocker | [[Category: Pieters R]] | ||
[[Category: | [[Category: Reymond J-L]] | ||
[[Category: Stocker A]] | |||
[[Category: Visini R]] | |||
Latest revision as of 07:20, 1 May 2024
Structural Insight into Divalent Galactoside Binding to Pseudomonas aeruginosa lectin LecA
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