3wsa: Difference between revisions
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==The Tuberculosis Drug SQ109 Inhibits Trypanosoma cruzi Cell Proliferation and acts Synergistically with Posaconazole== | ==The Tuberculosis Drug SQ109 Inhibits Trypanosoma cruzi Cell Proliferation and acts Synergistically with Posaconazole== | ||
<StructureSection load='3wsa' size='340' side='right' caption='[[3wsa]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='3wsa' size='340' side='right'caption='[[3wsa]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3wsa]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WSA OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[3wsa]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WSA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WSA FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RWZ:N-[(2Z)-3,7-DIMETHYLOCTA-2,6-DIEN-1-YL]-N-[(1R,3S,5R,7R)-TRICYCLO[3.3.1.1~3,7~]DEC-2-YL]ETHANE-1,2-DIAMINE'>RWZ</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RWZ:N-[(2Z)-3,7-DIMETHYLOCTA-2,6-DIEN-1-YL]-N-[(1R,3S,5R,7R)-TRICYCLO[3.3.1.1~3,7~]DEC-2-YL]ETHANE-1,2-DIAMINE'>RWZ</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wsa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wsa OCA], [https://pdbe.org/3wsa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wsa RCSB], [https://www.ebi.ac.uk/pdbsum/3wsa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wsa ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/FDFT_HUMAN FDFT_HUMAN] | |||
==See Also== | |||
*[[Squalene synthase|Squalene synthase]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Guo | [[Category: Large Structures]] | ||
[[Category: Huang | [[Category: Guo RT]] | ||
[[Category: Li | [[Category: Huang CH]] | ||
[[Category: Oldfield | [[Category: Li Q]] | ||
[[Category: Shang | [[Category: Oldfield E]] | ||
[[Category: Shang N]] | |||
Latest revision as of 13:25, 8 November 2023
The Tuberculosis Drug SQ109 Inhibits Trypanosoma cruzi Cell Proliferation and acts Synergistically with Posaconazole
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