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| ==The crystal structure of Der p 1 allergen complexed with Fab fragment of mAb 5H8==
| | #REDIRECT [[5vcn]] This PDB entry is obsolete and replaced by 5vcn |
| <StructureSection load='4pp1' size='340' side='right' caption='[[4pp1]], [[Resolution|resolution]] 3.00Å' scene=''>
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| == Structural highlights ==
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| <table><tr><td colspan='2'>[[4pp1]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Dermatophagoides_pteronyssinus Dermatophagoides pteronyssinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PP1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PP1 FirstGlance]. <br>
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| </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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| <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rvw|3rvw]], [[3rvv|3rvv]], [[3rvx|3rvx]], [[4poz|4poz]], [[4pp2|4pp2]]</td></tr>
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| <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidase_1_(mite) Peptidase 1 (mite)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.65 3.4.22.65] </span></td></tr>
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| <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pp1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pp1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pp1 RCSB], [http://www.ebi.ac.uk/pdbsum/4pp1 PDBsum]</span></td></tr>
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| </table>
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| == Function ==
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| [[http://www.uniprot.org/uniprot/PEPT1_DERPT PEPT1_DERPT]] Thiol protease, with a preference for substrates with a large hydrophobic side chain in the P2 position, or with basic residues.
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| __TOC__
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| </StructureSection>
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| [[Category: Dermatophagoides pteronyssinus]]
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| [[Category: Chapman, M D]]
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| [[Category: Chruszcz, M]]
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| [[Category: Glesner, J]]
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| [[Category: Majorek, K A]]
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| [[Category: Minor, W]]
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| [[Category: Offermann, L R]]
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| [[Category: Osinski, S]]
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| [[Category: Osinski, T]]
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| [[Category: Pomes, A]]
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| [[Category: Vailes, L D]]
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| [[Category: Allergen]]
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| [[Category: Antibody]]
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| [[Category: Immune system]]
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