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[[Image:2uvd.gif|left|200px]]


{{Structure
==The crystal structure of a 3-oxoacyl-(acyl carrier protein) reductase from Bacillus anthracis (BA3989)==
|PDB= 2uvd |SIZE=350|CAPTION= <scene name='initialview01'>2uvd</scene>, resolution 2.40&Aring;
<StructureSection load='2uvd' size='340' side='right'caption='[[2uvd]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2uvd]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._Ames Bacillus anthracis str. Ames]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UVD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UVD FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/3-oxoacyl-[acyl-carrier-protein]_reductase 3-oxoacyl-[acyl-carrier-protein] reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.100 1.1.1.100]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uvd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uvd OCA], [https://pdbe.org/2uvd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uvd RCSB], [https://www.ebi.ac.uk/pdbsum/2uvd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uvd ProSAT]</span></td></tr>
}}
</table>
 
== Function ==
'''THE CRYSTAL STRUCTURE OF A 3-OXOACYL-(ACYL CARRIER PROTEIN) REDUCTASE FROM BACILLUS ANTHRACIS (BA3989)'''
[https://www.uniprot.org/uniprot/A0A6L7H0J7_BACAN A0A6L7H0J7_BACAN] Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.[RuleBase:RU366074]
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
2UVD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UVD OCA].  
  <jmolCheckbox>
[[Category: 3-oxoacyl-[acyl-carrier-protein] reductase]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uv/2uvd_consurf.spt"</scriptWhenChecked>
[[Category: Bacillus anthracis]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Single protein]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Berrow, N S.]]
  </jmolCheckbox>
[[Category: Carter, L G.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2uvd ConSurf].
[[Category: Esnouf, R M.]]
<div style="clear:both"></div>
[[Category: Harlos, K.]]
__TOC__
[[Category: Nettleship, J E.]]
</StructureSection>
[[Category: Oppf, Oxford Protein Production Facility.]]
[[Category: Bacillus anthracis str. Ames]]
[[Category: Owens, R J.]]
[[Category: Large Structures]]
[[Category: Sainsbury, S.]]
[[Category: Berrow NS]]
[[Category: Spine, Structural Proteomics in Europe.]]
[[Category: Carter LG]]
[[Category: Stuart, D I.]]
[[Category: Esnouf RM]]
[[Category: Walter, T S.]]
[[Category: Harlos K]]
[[Category: Wilson, K S.]]
[[Category: Nettleship JE]]
[[Category: Zaccai, N R.]]
[[Category: Owens RJ]]
[[Category: 3-oxoacyl-(acyl carrier protein) reductase]]
[[Category: Sainsbury S]]
[[Category: beta-ketoacyl-(acyl carrier protein) reductase]]
[[Category: Stuart DI]]
[[Category: fabg]]
[[Category: Walter TS]]
[[Category: fatty acid biosynthesis]]
[[Category: Wilson KS]]
[[Category: lipid synthesis]]
[[Category: Zaccai NR]]
[[Category: nadp]]
[[Category: oppf]]
[[Category: oxford protein production facility]]
[[Category: oxidoreductase]]
[[Category: short-chain dehydrogenase/reductase (sdr)]]
[[Category: structural genomic]]
[[Category: structural proteomics in europe (spine)]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:40:09 2008''

Latest revision as of 14:55, 13 December 2023

The crystal structure of a 3-oxoacyl-(acyl carrier protein) reductase from Bacillus anthracis (BA3989)

2uvd, resolution 2.40Å

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