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==Structure of the parainfluenza virus 5 nucleocapsid-RNA complex: an insight into paramyxovirus polymerase activity==
==Structure of the parainfluenza virus 5 nucleocapsid-RNA complex: an insight into paramyxovirus polymerase activity==
<StructureSection load='4xjn' size='340' side='right' caption='[[4xjn]], [[Resolution|resolution]] 3.11&Aring;' scene=''>
<StructureSection load='4xjn' size='340' side='right'caption='[[4xjn]], [[Resolution|resolution]] 3.11&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4xjn]] is a 14 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XJN FirstGlance]. <br>
<table><tr><td colspan='2'>[[4xjn]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Mammalian_orthorubulavirus_5 Mammalian orthorubulavirus 5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XJN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PB:LEAD+(II)+ION'>PB</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.11&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xjn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xjn RCSB], [http://www.ebi.ac.uk/pdbsum/4xjn PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PB:LEAD+(II)+ION'>PB</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xjn OCA], [https://pdbe.org/4xjn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xjn RCSB], [https://www.ebi.ac.uk/pdbsum/4xjn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xjn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/W5QKM4_9PARA W5QKM4_9PARA]] Encapsidates the genome, protecting it from nucleases.[RuleBase:RU361245]
[https://www.uniprot.org/uniprot/NCAP_PIV5 NCAP_PIV5] Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4xjn" style="background-color:#fffaf0;"></div>
==See Also==
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Alayyoubi, M]]
[[Category: Escherichia coli]]
[[Category: Kors, C A]]
[[Category: Large Structures]]
[[Category: Lamb, R A]]
[[Category: Mammalian orthorubulavirus 5]]
[[Category: Leser, G P]]
[[Category: Alayyoubi M]]
[[Category: Complex]]
[[Category: Kors CA]]
[[Category: Nucleocapsid]]
[[Category: Lamb RA]]
[[Category: Piv5]]
[[Category: Leser GP]]
[[Category: Rna]]